Sun-Young Kong
Chung-Ang University
11 Papers
33 Citations
Sun-Young Kong is an academic researcher from Chung-Ang University. The author has contributed to research in topics: Neural stem cell & Neurogenesis. The author has an hindex of 7, co-authored 11 publications.
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Papers
Kuwanon V Inhibits Proliferation, Promotes Cell Survival and Increases Neurogenesis of Neural Stem Cells
Sun-Young Kong,Min-Hye Park,Mina Lee,Jae-Ouk Kim,Ha-Rim Lee,Byung Woo Han,Clive N. Svendsen,Sang Hyun Sung,Hyun-Jung Kim +8 more
TL;DR: Kuwanon V (KWV), which was isolated from the mulberry tree (Morus bombycis) root, increased neurogenesis in rat NSCs and may be considered as a new drug candidate that can regenerate or protect neurons in neurodegenerative diseases.
The histone demethylase KDM5A is required for the repression of astrocytogenesis and regulated by the translational machinery in neural progenitor cells
TL;DR: Treatment of NPCs with the cercosporamide, a MAPK‐interacting kinases inhibitor, reduced eIF4E phosphorylation and KDM5A protein expression, increased GFAP levels, and enhanced astrocytogenesis, suggesting that K DM5A is a key regulator that maintains NPCs in an undifferentiated state by repressing astroCytogenesis and that its expression is translationally controlled during astroicyte differentiation.
39
Antidepressants for neuro-regeneration: from depression to Alzheimer’s disease
TL;DR: Clinical trial data support that antidepressants have potential to treat Alzheimer’s disease and new potential functions of antidepressants in the treatment of neurodegenerative will be introduced.
35
Aminopropyl carbazole analogues as potent enhancers of neurogenesis
Hyejin Yoon,Sun-Young Kong,Min-Hye Park,Yongsung Cho,Sungeun Kim,Jae-Yeon Shin,Sunghye Jung,Jiyoun Lee,Farhanullah,Hyun-Jung Kim,Jeewoo Lee +10 more
TL;DR: This report has developed and screened 25 aminopropyl carbazole derivatives that can enhance neurogenesis of cultured neural stem cells and demonstrated an excellent proneurogenic and neuroprotective activity with no apparent toxicity.
32
Cell density-dependent differential proliferation of neural stem cells on omnidirectional nanopore-arrayed surface.
Kyoung Je Cha,Sun-Young Kong,Ji Soo Lee,Hyung Woo Kim,Jae-Yeon Shin,Moonwoo La,Moonwoo La,Byung Woo Han,Dong Sung Kim,Hyun-Jung Kim +9 more
TL;DR: Data demonstrate that ONAS maintains NSCs as undifferentiated while retaining multipotency and is a better topography for culturing low density N SCs.