Suhyun Lee
UPRRP College of Natural Sciences
16 Papers
8 Citations
Suhyun Lee is an academic researcher from UPRRP College of Natural Sciences. The author has contributed to research in topics: Heme oxygenase & Nitric oxide synthase. The author has an hindex of 9, co-authored 15 publications. Previous affiliations of Suhyun Lee include Kangwon National University.
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Papers
Sappanone A exhibits anti-inflammatory effects via modulation of Nrf2 and NF-κB.
Suhyun Lee,Sol-Yip Choi,Young-Yeon Choo,Okwha Kim,Phuong Thao Tran,Cuong To Dao,Byung Sun Min,Jeong-Hyung Lee +7 more
TL;DR: The findings suggest that sappanone A exerts its anti-inflammatory effect by modulating the Nrf2 and NF-κB pathways, and may be a valuable compound to prevent or treat inflammatory diseases.
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Epigenetic regulation of TGF-β-induced EMT by JMJD3/KDM6B histone H3K27 demethylase.
Suhyun Lee,Okhwa Kim,Hyo Jin Kim,Cheol Hwangbo,Jeong-Hyung Lee +4 more
- 26 Feb 2021
TL;DR: In this article, the authors demonstrate that Jumonji domain containing-3 (JMJD3) also called KDM6B promotes TGF-β-mediated Smad activation and EMT in Ras-activated lung cancer cells.
Eupatolide inhibits PDGF-induced proliferation and migration of aortic smooth muscle cells through ROS-dependent heme oxygenase-1 induction.
TL;DR: Findings suggest that EuTL could suppress PDGF‐induced proliferation and migration of VSMCs through HO‐1 induction via ROS‐Nrf2 pathway and may be a potential HO-1 inducer for preventing or treating vascular diseases.
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Caffeoylglycolic acid methyl ester, a major constituent of sorghum, exhibits anti-inflammatory activity via the Nrf2/heme oxygenase-1 pathway
Young-Yeon Choo,Suhyun Lee,Phi Hung Nguyen,Wanju Lee,Mi-Hee Woo,Byung Sun Min,Jeong-Hyung Lee +6 more
TL;DR: Findings suggest that caffeoylglycolic acid methyl ester exerts an anti-inflammatory effect through the Nrf2/HO-1 pathway, and may be a potential HO-1 inducer for preventing or treating inflammatory diseases.
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Ganomycin I from Ganoderma lucidum attenuates RANKL-mediated osteoclastogenesis by inhibiting MAPKs and NFATc1
Phuong Thao Tran,Nguyen Tien Dat,Nguyen Hai Dang,Pham Van Cuong,Suhyun Lee,Cheol Hwangbo,Chau Van Minh,Jeong-Hyung Lee +7 more
TL;DR: It is suggested that GMI can attenuate osteoclast formation by suppressing RANKL-mediated MAPKs and NFATc1 signaling pathways and the anti-osteoclastogenic activity of GMI may extend the understanding of molecular mechanisms underlying biological activities and pharmacological use of G. lucidum as a traditional anti-OSTeoporotic medicine.
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