Sugimoto S
Nippon Medical School
15 Papers
50 Citations
Sugimoto S is an academic researcher from Nippon Medical School. The author has contributed to research in topics: Ischemia & Trapidil. The author has an hindex of 4, co-authored 15 publications.
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Papers
Susceptibility to ischemic insult in hypertensive rats: correlation between degree of ischemia and hypertension.
Yasuo Katayama,Sugimoto S,Kenji Inamura,Toshiyuki Soeda,Jun Shimizu,Suzuki S,Atsushi Nagazumi,Akiro Terashi +7 more
TL;DR: The degree of hypertension that produces high vulnerability to stroke and severe damage to the brain after ischemic insult is indicated as beginning at about 180 mmHg.
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•Journal Article
[Protective effect of thromboxane A2 synthetase inhibitor (trapidil) on acutely-induced cerebral ischemia].
TL;DR: The experimental study presented was undertaken to evaluate the role of thromboxane A2 contributing to aggravating cerebral ischemia, and to examine the effect of a thromboxesized A2 synthetase inhibitor, trapidil on cerebral isChemia.
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Experimental Cerebral Ischemia after Bilateral Common Carotid Artery Ligation in SHRSP, SHRSR and Wistar Rats
Yasuo Katayama,Akiro Terashi,Sugimoto S,Masaaki Mizoguchi,Kenji Inamura,Toshiyuki Soeda,Jun Shimizu,Suzuki S,Hiroaki Minamizawa,Memezawa H,Atsushi Nagazumi +10 more
TL;DR: Three different pressure groups of rats, stroke-prone spontaneously hypertensive rats (SHRSP), stroke-resistant SHR (SHRSR), and Wistar rats (WR, 120-160 mmHg) were used to investigate the effect of prior existing hypertension on the severity of brain damage induced by ischemia.
7
•Journal Article
[Effects of S-adenosyl-L-methionine on experimental cerebral ischemia].
Yasuo Katayama,Jun Shimizu,Memezawa H,Minamisawa H,Kenji Inamura,M. Mizoguchi,Sugimoto S,Nagazumi A,Akiro Terashi +8 more
TL;DR: It is indicated that S-adenosyl-L-methionine (SAMe) protected energy failure in ischemia and accelerated recovery from ischemIA and this agent is beneficial for treatment of cerebral ischemies in the acute stage.
5
•Journal Article
Arachidonic acid-induced brain ischaemia: different severity between stroke-resistant spontaneously hypertensive rats and Wistar-Kyoto rats.
Memezawa H,Yasuo Katayama,Sugimoto S,Kenji Inamura,Jun Shimizu,T. Soeda,Suzuki S,Akiro Terashi +7 more
TL;DR: Electron microscopic observation revealed more severe endothelial damage, mitochondrial swelling and perivascular oedema and earlier thrombus formation in SHRSR than in WKY rats.
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