Sue E. Blackwell
University of Iowa
29 Papers
82 Citations
Sue E. Blackwell is an academic researcher from University of Iowa. The author has contributed to research in topics: CpG Oligodeoxynucleotide & CpG site. The author has an hindex of 13, co-authored 29 publications. Previous affiliations of Sue E. Blackwell include Roy J. and Lucille A. Carver College of Medicine & University of Iowa Hospitals and Clinics.
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Papers
Delineation of a CpG Phosphorothioate Oligodeoxynucleotide for Activating Primate Immune Responses In Vitro and In Vivo
Gunther Hartmann,Risini D. Weeratna,Zuhair K. Ballas,Zuhair K. Ballas,Paul J. Payette,Sue E. Blackwell,Irma Herawati Suparto,Wendy L. Rasmussen,Marianella Waldschmidt,Dondin Sajuthi,Robert H. Purcell,Heather L. Davis,Heather L. Davis,Arthur M. Krieg,Arthur M. Krieg,Arthur M. Krieg +15 more
TL;DR: An optimal human CpG motif for phosphorothioate ODN that is a candidate human vaccine adjuvant is reported and developed 15 times higher anti-hepatitis B Ab titers than those receiving vaccine alone.
B-chronic lymphocytic leukemia cells and other B cells can produce granzyme B and gain cytotoxic potential after interleukin-21-based activation.
Bernd Jahrsdörfer,Sue E. Blackwell,James E. Wooldridge,Jian Huang,Melinda W. Andreski,Laura S. Jacobus,Christiana M. Taylor,George J. Weiner +7 more
TL;DR: The ability to induce production of functional granzyme B by B cells could open new approaches to the therapy of B-CLL and other B-cell malignancies and have significant implications for the understanding of the role of B cells for immune regulation and for a variety of immune phenomena.
156
Human Plasmacytoid Dendritic Cell Function: Inhibition of IFN-α Secretion and Modulation of Immune Phenotype by Vasoactive Intestinal Peptide
TL;DR: Results strongly suggest that VIP regulates the immunological function of human PDC, and may be involved in the modulation of immune responses to viral infections as well as in the maintenance of immune tolerance.
37
Good prognosis cytogenetics in B-cell chronic lymphocytic leukemia is associated in vitro with low susceptibility to apoptosis and enhanced immunogenicity.
Bernd Jahrsdörfer,James E. Wooldridge,Sue E. Blackwell,Christiana M. Taylor,Brian K. Link,George J. Weiner +5 more
TL;DR: The data indicate that good prognosis cytogenetics correlates with less spontaneous apoptosis but greater in vitro immunogenicity, which could have significant implications on the design of future therapeutic approaches in patients with CLL, and the likelihood of response based on cytogenetic principles.
29
Construction of a human chromosome 4 YAC pool and analysis of artificial chromosome stability
Heidi Major Sleister,Kathleen A. Mills,Sue E. Blackwell,Ann M. Killary,Jeffrey C. Murray,Robert E. Malone +5 more
TL;DR: The majority of YACs examined are one to two orders of magnitude less stable than authentic yeast chromosomes, and the results suggest that increasing the length of an artificial chromosome improves its mitotic stability.