Subeer S. Majumdar
Department of Biotechnology
117 Papers
532 Citations
Subeer S. Majumdar is an academic researcher from Department of Biotechnology. The author has contributed to research in topics: Sertoli cell & Spermatogenesis. The author has an hindex of 24, co-authored 106 publications. Previous affiliations of Subeer S. Majumdar include Southern Illinois University Carbondale & Jawaharlal Nehru University.
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Papers
Mechanism of lipid induced insulin resistance: activated PKCε is a key regulator.
Suman Dasgupta,Sushmita Bhattacharya,Sudipta Maitra,Durba Pal,Subeer S. Majumdar,Asis Datta,Samir Bhattacharya,Samir Bhattacharya +7 more
TL;DR: It is reported here that central to this mechanism is the phosphorylation of PKCε by FAs, which resulted in the attenuation of HMGA1 driven IR transcription that compromised insulin signaling and sensitivity.
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Abnormal V(D)J Recombination of T Cell Receptor β Locus in SMAR1 Transgenic Mice
Ruchika Kaul-Ghanekar,Subeer S. Majumdar,Archana Jalota,Neerja Gulati,Neetu Dubey,Bhaskar Saha,Samit Chattopadhyay +6 more
TL;DR: Results indicate that SMAR1 plays an important role in the regulation of T cell development as well as V(D)J recombination besides maintaining the architecture of the lymphoid organs.
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Procedures for the isolation and culture of Sertoli cells from the testes of infant, juvenile, and adult rhesus monkeys (Macaca mulatta).
TL;DR: The establishment of conditions for the culture of infant, juvenile, and adult Sc from the rhesus monkey will provide a model for study of the postnatal ontogeny of Sc function in higher primates.
Hormone induced differential transcriptome analysis of Sertoli cells during postnatal maturation of rat testes.
TL;DR: Compared the differential transcriptional profile of Sc isolated and cultured from immature, maturing and mature rat testes revealed that immature Sc express genes involved in cellular growth, metabolism, chemokines, cell division, MAPK and Wnt pathways, while mature Sc are more specialized expressing genesinvolved in glucose metabolism, phagocytosis, insulin signaling and cytoskeleton structuring.
An efficient method for generating a germ cell depleted animal model for studies related to spermatogonial stem cell transplantation
Nirmalya Ganguli,Neerja Wadhwa,Abul Usmani,Neetu Kunj,Nilanjana Ganguli,Rajesh Kumar Sarkar,Soma M. Ghorai,Subeer S. Majumdar +7 more
TL;DR: An efficient method of generating a germ cell-depleted animal model by using a lower dose of busulfan, injected through two diagonally opposite sites in the testis, which allows efficient colonization of transplanted SSC resulting in a remarkably higher proportion of donor-derived offspring generation.