6 Papers
1 Citations
Su Yan is an academic researcher from Genome Institute of Singapore. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 1, co-authored 2 publications.
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Papers
High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancer
Iain Beehuat Tan,Simeen Malik,Kalpana Ramnarayanan,John R. McPherson,Dan Liang Ho,Yuka Suzuki,Sarah Boonhsui Ng,Su Yan,Kiat Hon Lim,Dennis Koh,Chew Min Hoe,Chung Yip Chan,Rachel Ten,Brian K. P. Goh,Alexander Yf Chung,Joanna Tan,Cheryl Xueli Chan,Su Ting Tay,Lezhava Alexander,Niranjan Nagarajan,Axel M. Hillmer,Choon Leong Tang,Clarinda Chua,Bin Tean Teh,Steve Rozen,Patrick Tan +25 more
TL;DR: High genomic concordance of primary tumor and metastasis, with a thick common trunk and smaller genomic branches in general support of the linear progression model in most patients with liver-limited mCRC is pointed to.
Evaluation of health-related quality of life and influencing factors in patients with Crohn disease
TL;DR: Depression, anxiety, disease activity, complications, and nutritional status were predictive factors of decreased HRQOL in patients with CD.
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Identification of HAGHL as a novel metabolic oncogene regulating human colorectal cancer progression
Yan Xu,Xiao-Jun Zhou,Ling Gao,Su Yan,Zhenyun Li,Da-Ling Zhang,Jianhong Pu,Shitao Zou,Zhongqi Mao +8 more
TL;DR: It is suggested that HAGHL acts as a novel metabolic oncogene and demonstrate the underlying mechanism by which H AGHL regulates CRC progression, highlighting its utility as a diagnostic and prognostic factor and as a potential therapeutic target for the treatment of CRC.
2
Abstract 5725: Systematic identification of tumour-specific neoantigens(by whole-genome sequencing) and correlation between tumour neoantigen burden, PD-L1 expression and immune infiltrates in 158Asian colorectal cancers
Si-Lin Koo,Joe Poh Sheng Yeong,Andy Nguyen,Clarinda Chua,J. Zachary Sanborn,Steve Benz,Wah Siew Tan,Choong Leong Tang,Su Yan,Min Hoe Chew,Brian K. P. Goh,Chung Yip Chan,Xiao Qing Koh,Alexander Lezhava,Tony Kiat Hon Lim,Shahrooz Rabizadeh,Anders Jacobsen Skanderup,Iain Beehuat Tan +17 more
TL;DR: There is substantial variability in the neoantigen landscape amongst MSI & MSS CRCs, and Histopathological correlations between extent of immune infiltrates in fixed tissues, tumour PD-L1 expression and neoepitopes is ongoing.
1
Bile Reflux Gastritis: Insights into Pathogenesis, Relevant Factors, Carcinomatous Risk, Diagnosis, and Management
TL;DR: Advances in techniques, especially extensive applications of endoscopy and chemical analysis of reflux contents, have improved the authors' ability to identify the occurrence of this disease as well as distinguishing physiological reflux from pathological reflux.