Stuart J. Morrow
University of Auckland
5 Papers
12 Citations
Stuart J. Morrow is an academic researcher from University of Auckland. The author has contributed to research in topics: Capillary electrophoresis & Inductively coupled plasma mass spectrometry. The author has an hindex of 4, co-authored 5 publications.
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Papers
Metallomic study on the metabolism of RAPTA-C and cisplatin in cell culture medium and its impact on cell accumulation
TL;DR: RAPTA-C was found to be more inert to extracellular reactions than cisplatin which could be used to rationalise the observed cellular uptake patterns and it is demonstrated that cancer cells have an influence on metal species distribution in the cell culture medium over time.
An approach to recombinantly produce mature grape polyphenol oxidase.
Yu Li,Mark-Anthony McLarin,Martin Middleditch,Stuart J. Morrow,Paul A. Kilmartin,Ivanhoe K. H. Leung +5 more
TL;DR: This work describes the production of the mature form of Shine Muscat grape PPO by using an Escherichia coli expression system and optimised the purification procedure to obtain pure and active recombinant enzymes and characterised the catalytic efficiency of the recombinant grape P PO by using ultraviolet/visible (UV/Vis) spectrophotometry.
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Gel electrophoresis in combination with laser ablation–inductively coupled plasma mass spectrometry to quantify the interaction of cisplatin with human serum albumin
TL;DR: A method based on SDS‐PAGE separation and laser ablation–inductively coupled plasma‐mass spectrometry (LA–ICP‐MS) for platinum detection in the reaction between human serum albumin (HSA) and cisplatin is presented.
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Cobalt complexes as internal standards for capillary zone electrophoresis–mass spectrometry studies in biological inorganic chemistry
TL;DR: In general, employing Co complexes resulted in improved data sets, particularly with regard to the migration times and peak areas, which resulted, for example, in higher linear ranges for the quantification of cisplatin.
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Hyphenation of capillary electrophoresis to inductively coupled plasma mass spectrometry with a modified coaxial sheath-flow interface.
TL;DR: In a set of proof-of-principle experiments employing the anticancer agent cisplatin it was demonstrated that the signal to noise response and sensitivity were considerably improved leading to detection limits for 195Pt of 0.08 μM.
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