Stuart Craig
Peter MacCallum Cancer Centre
3 Papers
Stuart Craig is an academic researcher from Peter MacCallum Cancer Centre. The author has contributed to research in topics: Medicine & Homologous recombination. The author has an hindex of 1, co-authored 1 publications.
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Papers
Multiomic analysis of homologous recombination-deficient end-stage high-grade serous ovarian cancer
Nikki Burdett,Madelynne O Willis,Kathryn Alsop,Allison L. Hunt,Ahwan Pandey,Phineas T. Hamilton,Tamara Abulez,Xuan Liu,Therese Hoang,Stuart Craig,Sian Fereday,Joy Hendley,Dale W. Garsed,Katy Milne,Shreena Kalaria,Ashley Marshall,Brian L. Hood,Katlin Wilson,Kelly A. Conrads,Kathleen I. Pishas,Sumitra Ananda,Clare L. Scott,Yoland Antill,Orla McNally,Linda Mileshkin,Anne Hamilton,George Au-Yeung,Lisa Devereux,Heather Thorne,Andrea Bild,D. Nicholas Bateman,G. Larry Maxwell,Jeffrey T. Chang,Thomas P. Conrads,Brad H. Nelson,David D.L. Bowtell,Elizabeth L. Christie +36 more
TL;DR: Diverse evolutionary changes within HGSC that evade therapy and ultimately overwhelm individual patients are highlighted, including reversion mutations and HR restoration by other means.
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Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene
Marcus Lefebure,Marcus Lefebure,Richard W. Tothill,Richard W. Tothill,Elizabeth Kruse,Edwin D. Hawkins,Jake Shortt,Geoffrey M. Matthews,Gareth P. Gregory,Benjamin P. Martin,Madison J. Kelly,Izabela Todorovski,Maria A. Doyle,Richard Lupat,Jason Li,Jan Schroeder,Meaghan Wall,Stuart Craig,Gretchen Poortinga,Donald P. Cameron,Megan J. Bywater,Lev Kats,Lev Kats,Micah D. Gearhart,Vivian J. Bardwell,Ross A. Dickins,Ross D. Hannan,Ross D. Hannan,Anthony T. Papenfuss,Anthony T. Papenfuss,Anthony T. Papenfuss,Ricky W. Johnstone,Ricky W. Johnstone +32 more
TL;DR: This work sequences spontaneously arising Eμ-Myc lymphomas to define transgene architecture, somatic mutations, and structural alterations and demonstrates a functional in vivo role for Bcor in suppressing tumorigenesis.
TRACEBACK: Testing of Historical Tubo-Ovarian Cancer Patients for Hereditary Risk Genes as a Cancer Prevention Strategy in Family Members
Rachel Delahunty,Linh Nguyen,Stuart Craig,Belinda Creighton,Dinuka Ariyaratne,Dale W. Garsed,Elizabeth L. Christie,Sian Fereday,Lesley Andrews,Alexandra Lewis,Sharne Limb,Ahwan Pandey,Joy Hendley,Nadia Traficante,Natalia Carvajal,Amanda B. Spurdle,Bryony A. Thompson,Michael T. Parsons,Victoria Beshay,Mila Volcheck,Timothy Semple,Richard Lupat,Ken Doig,Jiaan Yu,Xiao Qing Chen,Anna Marsh,Christopher G. Love,Sanela Bilic,M. V. Beilin,Cassandra B. Nichols,Christina Greer,Yeh Chen Lee,Sue Gerty,Lynette Gill,Emma Newton,Julie Howard,Rachel Williams,Christie Norris,Andrew N. Stephens,Erin Tutty,Courtney Smyth,S O’Connell,Tom Jobling,Colin J.R. Stewart,Adeline Tan,Stephen B. Fox,Nicholas Pachter,Jason Li,Jason Ellul,Gisela Mir Arnau,Mary-Anne Young,Louisa G. Gordon,Laura E Forrest,Marion Harris,Kathleen Livingstone,Jane Hill,Georgia Chenevix-Trench,Paul A. Cohen,Penelope M. Webb,Michael Friedlander,Paul A. James,David D.L. Bowtell,Kathryn Alsop +62 more
TL;DR: Rec retrospective genetic testing to identify PVs in previously untested deceased probands with TOC is demonstrated to be feasible, overcame ethical and logistic challenges, and allows identification of at-risk families for cancer prevention.