Stuart Avery
Agency for Science, Technology and Research
11 Papers
78 Citations
Stuart Avery is an academic researcher from Agency for Science, Technology and Research. The author has contributed to research in topics: Embryonic stem cell & Stem cell. The author has an hindex of 8, co-authored 11 publications. Previous affiliations of Stuart Avery include University of Sheffield.
Chat about Author
Papers
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage
Katherine Amps,Peter W. Andrews,George Anyfantis,Lyle Armstrong,Stuart Avery,Hossein Baharvand,Julie C. Baker,Duncan Baker,Maria D. Barbadillo Muñoz,Stephen J. Beil,Nissim Benvenisty,Dalit Ben-Yosef,Juan Carlos Biancotti,Alexis Bosman,Romulo M. Brena,Daniel R. Brison,Gunilla Caisander,Marãa V. Camarasa,Jieming Chen,Eric Chiao,Young Min Choi,Andre Choo,D.M. Collins,Alan Colman,Jeremy M. Crook,George Q. Daley,Anne Dalton,Paul A. De Sousa,Chris Denning,J.M. Downie,Petr Dvorak,Karen Dyer Montgomery,Anis Feki,Angela Ford,Victoria Fox,Ana Maria Fraga,Tzvia Frumkin,Lin Ge,Paul J. Gokhale,Tamar Golan-Lev,Hamid Gourabi,Michal Gropp,Lu GuangXiu,Aleš Hampl,Katie Harron,Lyn Healy,Wishva Herath,Frida Holm,Outi Hovatta,Johan Hyllner,Maneesha S. Inamdar,Astrid K. Irwanto,Tetsuya Ishii,Marisa Jaconi,Ying Jin,Susan J. Kimber,Sergey Kiselev,Barbara B. Knowles,Oded Kopper,Valeri Kukharenko,Anver Kuliev,Maria A. Lagarkova,Peter W. Laird,Majlinda Lako,Andrew L. Laslett,Neta Lavon,Dong Ryul Lee,Jeoung Eun Lee,Chunliang Li,Linda S. Lim,Tenneille Ludwig,Yu Ma,Edna Maltby,Ileana Mateizel,Yoav Mayshar,Maria Mileikovsky,Stephen L. Minger,Takamichi Miyazaki,Shin Yong Moon,Harry Moore,Christine L. Mummery,Andras Nagy,Norio Nakatsuji,Kavita Narwani,Steve Oh,Sun Kyung Oh,Cia Olson,Timo Otonkoski,Fei Pan,In-Hyun Park,Steve Pells,Martin F. Pera,Lygia da Veiga Pereira,Ouyang Qi,Grace Selva Raj,Benjamin Reubinoff,Alan Robins,Paul Robson,Janet Rossant,Ghasem Hosseini Salekdeh,Thomas C. Schulz,Karen Sermon,Jameelah Sheik Mohamed,Hui Shen,Eric S Sherrer,Kuldip S. Sidhu,Shirani Sivarajah,Heli Skottman,Claudia Spits,Glyn Stacey,Raimund Strehl,Nick Strelchenko,Hirofumi Suemori,Bowen Sun,Riitta Suuronen,Kazutoshi Takahashi,Timo Tuuri,Parvathy Venu,Yuri Verlinsky,Dorien Ward-van Oostwaard,Daniel J. Weisenberger,Yue Wu,Shinya Yamanaka,Lorraine E. Young,Qi Zhou +124 more
TL;DR: Of these genes, BCL2L1 is a strong candidate for driving culture adaptation of ES cells, and single-nucleotide polymorphism analysis revealed that they included representatives of most major ethnic groups.
BCL-XL Mediates the Strong Selective Advantage of a 20q11.21 Amplification Commonly Found in Human Embryonic Stem Cell Cultures
Stuart Avery,Adam J. Hirst,Adam J. Hirst,Duncan Baker,Chin Yan Lim,Sharmini Alagaratnam,Rolf Inge Skotheim,Ragnhild A. Lothe,Martin F. Pera,Martin F. Pera,Alan Colman,Paul Robson,Peter W. Andrews,Barbara B. Knowles +13 more
TL;DR: It is shown that those containing this amplicon have higher population doubling rates, attributable to enhanced cell survival through resistance to apoptosis, and linking this mutation with malignant transformation.
163
The Regulation of Self-Renewal in Human Embryonic Stem Cells
TL;DR: A review of the mechanisms known to control self-renewal and pluripotency in hES cells provides a summary of the molecular mechanisms enabling this process are not fully characterized.
76
Sphingosine-1-Phosphate Mediates Transcriptional Regulation of Key Targets Associated with Survival, Proliferation, and Pluripotency in Human Embryonic Stem Cells
TL;DR: S1P regulated apoptosis through several BCL-2 family members, including BAX and BID, with increased expression of cell cycle progression genes associated with proliferation of hESC cultures, but gene expression associated with pluripotency was decreased with S1P treatment indicating that an increased rate of h ESC turnover may be balanced by an increased susceptibility to differentiate.
76
Mechanisms controlling self-renewal and pluripotency in human embryonic stem cells.
TL;DR: HUlnan eJnbryonic stelll cells (hESCs) are an inunensely powerful tool for studying early differentiation of hUtllan cell lineages in vitro and offer the prospective that banks of hESCs can generate specific cell phenotypes to a consistent quality for use in clinical treatments for a range of degenerative diseases.
4