An anchor deployment tool (30) includes a flexible outer tube (34), within which is positioned a flexible inner shaft (36), and a rotating deployment element (38) coupled to a distal end (39) of the shaft. The tool (30) is configured to provide an anchor storage area (40), which initially stores a plurality of tissue anchors (32), such that the inner shaft (36) passes through channels of the anchors along entire longitudinal lengths of the anchors (32), and the anchors are within the outer tube (34). The rotating deployment element (38) is configured to directly engage the anchors (32) in the anchor storage area (40) one at a time, advance each of the anchors while engaged in a distal direction, and deploy each of the anchors through the distal tube end (42) and into tissue of a subject. Other embodiments are also described.

Multiple anchor delivery tool

Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools.

Devices, systems, and methods for reshaping a heart valve annulus

Embodiments of the present disclosure provide a prosthetic heart valve and a heart valve delivery apparatus for delivery of the prosthetic heart valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. In one embodiment, a self-expanding valve comprises an expandable stent that is shaped to maintain the valve in the aortic annulus against axial without anchors or retaining devices that engage the surrounding tissue. A delivery apparatus for delivering s self-expanding prosthetic valve can be configured to allow controlled and precise deployment of the valve from a valve sheath so as to minimize or prevent jumping of the valve from the valve sheath.

Prosthetic heart valve and delivery apparatus

A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non- expandable type, or may be expandable from a compressed state to an expanded state. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment.

Rapid deployment prosthetic heart valve

A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.

Vascular implant and delivery system

Disclosed are methods, systems, and devices for the endovascular repair of cardiac valves, particularly the atrioventricular valves which inhibit back flow of blood from a heart ventricle during contraction The procedures described herein can be performed with interventional tools, guides and supporting catheters and other equipment introduced to the heart chambers from the patient's arterial or venous vasculature remote from the heart The interventional tools and other equipment may be introduced percutaneously or may be introduced via a surgical cut down, and then advanced from the remote access site through the vasculature until they reach the heart

Methods, systems and devices for cardiac valve repair

The invention provides devices, systems and methods for tissue approximation and repair at treatment sites. The devices, systems and methods of the invention will find use in a variety of therapeutic procedures, including endovascular, minimally-invasive, and open surgical procedures, and can be used in various anatomical regions, including the abdomen, thorax, cardiovascular system, heart, intestinal tract, stomach, urinary tract, bladder, lung, and other organs, vessels, and tissues. The invention is particularly useful in those procedures requiring minimally-invasive or endovascular access to remote tissue locations, where the instruments utilized must negotiate long, narrow, and tortuous pathways to the treatment site. In addition, many of the devices and systems of the invention are adapted to be reversible and removable from the patient at any point without interference with or trauma to internal tissues.

Gripper pusher mechanism for tissue apposition systems

The utility model discloses a device for replacing chordae tendineae, comprising a flexible patch and a proximal anchor-shaped object of a lobule connector, wherein the flexible patch is fixed on the partial upper surface of a flail lobule through the lobule connector comprising an extensible element pair mutually connected via a central connecting rod. The device further comprises a distal anchor-shaped object extended to and fixed on an end-joining point in a heart; and a flexible Tethered cord connected to the proximal and distal anchor-shaped objects and tensioned between the proximal and distal anchor-shaped objects. The procedures described herein can be performed with interventional tools, guides and supporting catheters and other equipment introduced to the heart chambers from the patient's arterial or venous vasculature remote from the heart. The interventional tools and other equipment may be introduced percutaneously or may be introduced via a surgical cut down, and then advanced from the remote access site through the vasculature until they reach the heart.

Device for replacing chordae tendineae

PROBLEM TO BE SOLVED: To provide devices, systems and methods for tissue approximation and repair requiring minimally-invasive or endovascular access to remote tissue locations to negotiate long, narrow and tortuous pathways to a treatment site.SOLUTION: Proximal element actuators 90A, 90B are moved so that proximal elements 16A, 16B are moved at a variety of angles and distances from the distal elements 18A, 18B. The proximal element actuators are pulled proximally and maintain the proximal elements in an intermediate position relative to the distal elements. Once the proximal elements are in a desired position, a shaft 12 and a coupling member 19 are decoupled or separated so that proximal retraction of the proximal element actuators decouples or separates proximal element lines from the proximal elements. Thus, a fixation device 14 is left in place while the shaft, the proximal element actuators and other parts are removed from a site of operation.SELECTED DRAWING: Figure 15K

Gripper pusher for tissue apposition systems

System for fixation of leaflets of a heart valve

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