Steven Ringquist
University of Colorado Boulder
27 Papers
400 Citations
Steven Ringquist is an academic researcher from University of Colorado Boulder. The author has contributed to research in topics: Nucleic acid & Systematic evolution of ligands by exponential enrichment. The author has an hindex of 15, co-authored 27 publications. Previous affiliations of Steven Ringquist include OSI Pharmaceuticals.
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Papers
Translation initiation in Escherichia coli: sequences within the ribosome-binding site.
Steven Ringquist,Sidney Shinedling,Doug Barrick,Louis S. Green,Jonathan Binkley,Gary D. Stormo,Larry Gold +6 more
TL;DR: The translational roles of the Shine‐Dalgarno sequence, the initiation codon, the space between them, and the second codon have been studied and are consistent with a simple kinetic model in which a variety of rate constants contribute to the process of translation initiation.
433
High-affinity RNA ligands to Escherichia coli ribosomes and ribosomal protein S1: comparison of natural and unnatural binding sites.
TL;DR: High-affinity RNA ligand exhibited specificity for their respective targets, as well as conserved sequence and secondary structure reminiscent of naturally occurring, cis-acting mRNA elements.
122
The Escherichia coli chromosome contains specific, unmethylated dam and dcm sites.
TL;DR: Specific dam and dcm sites on the E. coli chromosome were found to be unmethylated in vivo by using pulsed-filed gel electrophoresis experiments scanning megabase regions of DNA, suggesting multiple protection mechanisms.
74
Patent
High affinity oligonucleotide ligands to growth factors
Penelope J. Toothman,Larry Gold,Nebojsa Janjic,Steven Ringquist,Nikos Pagratis +4 more
- 30 May 1996
TL;DR: In this article, the SELEX method was used to identify RNA and ssDNA ligands to TGFβ1 and PDGF identified by the SEleX (systematic evolution of ligands by exponential enrichment) method.
65
Patent
Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex
Larry Gold,Michael Willis,Tad Koch,Steven Ringquist,Kirk B. Jensen,Brent Boulder Atkinson +5 more
- 16 Sep 1994
TL;DR: In this paper, a method for identifying nucleic acid ligands to target molecules using the SELEX procedure where the candidate nucleic acids contain photoreactive groups and ligands identified thereby are claimed.
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