Steve Pells
University of Edinburgh
22 Papers
220 Citations
Steve Pells is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Embryonic stem cell & Stem cell. The author has an hindex of 16, co-authored 22 publications. Previous affiliations of Steve Pells include The Roslin Institute.
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Papers
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage
Katherine Amps,Peter W. Andrews,George Anyfantis,Lyle Armstrong,Stuart Avery,Hossein Baharvand,Julie C. Baker,Duncan Baker,Maria D. Barbadillo Muñoz,Stephen J. Beil,Nissim Benvenisty,Dalit Ben-Yosef,Juan Carlos Biancotti,Alexis Bosman,Romulo M. Brena,Daniel R. Brison,Gunilla Caisander,Marãa V. Camarasa,Jieming Chen,Eric Chiao,Young Min Choi,Andre Choo,D.M. Collins,Alan Colman,Jeremy M. Crook,George Q. Daley,Anne Dalton,Paul A. De Sousa,Chris Denning,J.M. Downie,Petr Dvorak,Karen Dyer Montgomery,Anis Feki,Angela Ford,Victoria Fox,Ana Maria Fraga,Tzvia Frumkin,Lin Ge,Paul J. Gokhale,Tamar Golan-Lev,Hamid Gourabi,Michal Gropp,Lu GuangXiu,Aleš Hampl,Katie Harron,Lyn Healy,Wishva Herath,Frida Holm,Outi Hovatta,Johan Hyllner,Maneesha S. Inamdar,Astrid K. Irwanto,Tetsuya Ishii,Marisa Jaconi,Ying Jin,Susan J. Kimber,Sergey Kiselev,Barbara B. Knowles,Oded Kopper,Valeri Kukharenko,Anver Kuliev,Maria A. Lagarkova,Peter W. Laird,Majlinda Lako,Andrew L. Laslett,Neta Lavon,Dong Ryul Lee,Jeoung Eun Lee,Chunliang Li,Linda S. Lim,Tenneille Ludwig,Yu Ma,Edna Maltby,Ileana Mateizel,Yoav Mayshar,Maria Mileikovsky,Stephen L. Minger,Takamichi Miyazaki,Shin Yong Moon,Harry Moore,Christine L. Mummery,Andras Nagy,Norio Nakatsuji,Kavita Narwani,Steve Oh,Sun Kyung Oh,Cia Olson,Timo Otonkoski,Fei Pan,In-Hyun Park,Steve Pells,Martin F. Pera,Lygia da Veiga Pereira,Ouyang Qi,Grace Selva Raj,Benjamin Reubinoff,Alan Robins,Paul Robson,Janet Rossant,Ghasem Hosseini Salekdeh,Thomas C. Schulz,Karen Sermon,Jameelah Sheik Mohamed,Hui Shen,Eric S Sherrer,Kuldip S. Sidhu,Shirani Sivarajah,Heli Skottman,Claudia Spits,Glyn Stacey,Raimund Strehl,Nick Strelchenko,Hirofumi Suemori,Bowen Sun,Riitta Suuronen,Kazutoshi Takahashi,Timo Tuuri,Parvathy Venu,Yuri Verlinsky,Dorien Ward-van Oostwaard,Daniel J. Weisenberger,Yue Wu,Shinya Yamanaka,Lorraine E. Young,Qi Zhou +124 more
TL;DR: Of these genes, BCL2L1 is a strong candidate for driving culture adaptation of ES cells, and single-nucleotide polymorphism analysis revealed that they included representatives of most major ethnic groups.
A thermoresponsive and chemically defined hydrogel for long-term culture of human embryonic stem cells
Rong Zhang,Heidi K. Mjoseng,Marieke A. Hoeve,Nina G. Bauer,Steve Pells,Rut Besseling,Srinivas Velugotla,Guilhem Tourniaire,Ria E. B. Kishen,Yanina Tsenkina,Chris Armit,Cairnan R. E. Duffy,Martina Helfen,Frank Edenhofer,Paul A. De Sousa,Mark Bradley +15 more
TL;DR: A family of chemically defined thermoresponsive synthetic hydrogels based on 2-(diethylamino)ethyl acrylate, which support long-term human embryonic stem cell growth and pluripotency over a period of 2–6 months are reported.
Developmentally-regulated expression of murine K-ras isoforms
Steve Pells,Maja Divjak,P Romanowski,H Impey,Nicholas J. Hawkins,Alan Richard Clarke,Martin L. Hooper,D. J. Williamson,D. J. Williamson,D. J. Williamson +9 more
TL;DR: K-rasA is induced during differentiation of pluripotent embryonal stem cells in vitro and its expression during early embryogenesis is limited temporally and spatially in a tissue-specific distribution which is largely maintained as an adult, suggesting a distinct biological role for p21K-raA.
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Multipotentiality of neuronal cells after spontaneous fusion with embryonic stem cells and nuclear reprogramming in vitro.
TL;DR: The results raise the intriguing possibility that ASCs shown to contribute to multiple tissues in blastocyst-injection studies may not contribute as a result of pluripotency, and instead contributions may arise from spontaneous fusion events in which phenotype is determined by either cytoplasmic dominance, nuclear reprogramming, or both.
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Elasticity of Human Embryonic Stem Cells as Determined by Atomic Force Microscopy
Róbert Kiss,Henry Bock,Steve Pells,Elisabetta Canetta,Ashok K. Adya,Andrew J. Moore,Paul A. De Sousa,Nicholas Willoughby +7 more
TL;DR: Differences in the elasticity of human embryonic stem cells are found, reflected by a broad range of Young's modulus (0.05-10 kPa), suggesting that elasticity could serve as the basis of a simple and efficient large scale purification/separation technique to discriminate subpopulations of hESCs.
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