Stephen M Shalet
National Health Service
395 Papers
5.7K Citations
Stephen M Shalet is an academic researcher from National Health Service. The author has contributed to research in topics: Medicine & Growth hormone deficiency. The author has an hindex of 88, co-authored 394 publications. Previous affiliations of Stephen M Shalet include Boston Children's Hospital.
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Papers
Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis
Andrew G Renehan,Marcel Zwahlen,Christoph E. Minder,Sarah T O'Dwyer,Stephen M Shalet,Matthias Egger,Matthias Egger +6 more
TL;DR: Circulating concentrations of IGF-I and IGFBP-3 are associated with an increased risk of common cancers, but associations are modest and vary between sites.
1.7K
Consensus guidelines for the diagnosis and treatment of growth hormone (GH) deficiency in childhood and adolescence: Summary statement of the GH research society
Kenneth M. Attie,Bengt-Åke Bengtsson,Sandra L. Blethen,Werner F. Blum,Fergus J. Cameron,Jean Claude Carel,Lena M. S. Carlsson,John J. Chipman,Jens Sandahl Christiansen,Peter E. Clayton,David R. Clemmons,Pinchas Cohen,Stenvert L. S. Drop,Kenji Fujieda,Ezio Ghigo,Raymond L. Hintz,Ken K. Y. Ho,Mbelenge Mapoko Ilondo,Hector Jasper,Bernd Jesussek,Anne Marie Kappelgaard,Zvi Laron,Barbara Lippe,Saul Malozowski,Primus E. Mullis,Sabine M P F de MuinckKeizer-Schrama,Yoshikazu Nishi,John S. Parks,Charlotte Phelps,Michael B. Ranke,Iain C.A.F. Robinson,Ron G. Rosenfeld,Susan R. Rose,Paul Saenger,Guissepe Saggese,Martin O. Savage,Stephen M Shalet,Pierre C. Sizonenko,Christian J. Strasburger,Katsuhiko Tachibana,Toshiaki Tanaka,Michael O. Thorner,Kerstin Albertsson Wikland,Zvi Zadik +43 more
Spermatogenesis After Cancer Treatment: Damage and Recovery
Sacha J Howell,Stephen M Shalet +1 more
TL;DR: The vast majority of men receiving procarbazine-containing regimens for the treatment of lymphomas are rendered permanently infertile, whereas treatment with doxorubicin hydrochloride (Adriamycin), bleomycin, vinblastine, and dacarbazine appears to have a significant advantage, with a return to normal fertility in the vastmajority of patients.
Clinical studies of multiple endocrine neoplasia type 1 (MEN1)
D Trump,B. Farren,C Wooding,J T Pang,G. M. Besser,K D Buchanan,C.R. Edwards,D A Heath,Charles E. Jackson,S. Jansen,K. Lips,John P. Monson,Domhnall J O'Halloran,Julian R. Sampson,Stephen M Shalet,M.H. Wheeler,A. Zink,Rajesh V. Thakker +17 more
TL;DR: Investigation of multiple endocrine neoplasia type 1 patients found that parathyroid tumours were the first manifestation of MEN1 in 87% of patients, and amongst the pituitary and pancreatic tumours, somatotrophinomas and gastrinomas were more common in patients above the age of 40 years, whilst insulinomas occurred more frequently in patients below the ageof 40 years.
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Hypopituitarism following external radiotherapy for pituitary tumours in adults.
TL;DR: There is a high incidence of anterior pituitary hormone deficiencies in patients treated surgically forpituitary tumours and the incidence increases after external radiotherapy and endocrine testing is recommended on an annual basis.
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