Stephen Hayes
University College Cork
6 Papers
12 Citations
Stephen Hayes is an academic researcher from University College Cork. The author has contributed to research in topics: Carbohydrate-binding module & Biology. The author has an hindex of 5, co-authored 5 publications.
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Papers
Metagenomic Approaches to Assess Bacteriophages in Various Environmental Niches.
TL;DR: The evolution of viral metagenomic methodologies is reviewed, as well as providing an overview of some of the most significant applications and findings in this field of research.
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Functional carbohydrate binding modules identified in evolved dits from siphophages infecting various Gram-positive bacteria.
Stephen Hayes,Renaud Vincentelli,Renaud Vincentelli,Jennifer Mahony,Arjen Nauta,Laurie Ramond,Laurie Ramond,Gabriele Andrea Lugli,Marco Ventura,Douwe van Sinderen,Christian Cambillau,Christian Cambillau,Christian Cambillau +12 more
TL;DR: The omnipresence of CBM domains in siphophages indicates their auxiliary role in infection, as they can assist in the specific recognition of and attachment to their host, thus ensuring a highly efficient and specific phage‐host adhesion process as a prelude to DNA injection.
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Biocidal inactivation of Lactococcus lactis bacteriophages: efficacy and targets of commonly used sanitizers
Stephen Hayes,James Murphy,Jennifer Mahony,Gabriele Andrea Lugli,Marco Ventura,Jean-Paul Noben,Charles M. A. P. Franz,Horst Neve,Arjen Nauta,Douwe van Sinderen +9 more
TL;DR: Rather than possessing resistance to specific biocides or biocide types, biocide-resistant phages tend to possess a broad tolerance to multiple classes of antimicrobial compounds.
Ubiquitous Carbohydrate Binding Modules Decorate 936 Lactococcal Siphophage Virions
Stephen Hayes,Jennifer Mahony,Renaud Vincentelli,Laurie Ramond,Arjen Nauta,Douwe van Sinderen,Christian Cambillau +6 more
TL;DR: Bioinformatic analysis of the structural proteins of 936 phages reveals that they incorporate binding modules which exhibit structural homology to those found in other lactococcal phage groups and beyond, indicating that phages utilize common structural “bricks” to enhance host binding capabilities.
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Identification of Dual Receptor Binding Protein Systems in Lactococcal 936 Group Phages.
Stephen Hayes,Yoan Duhoo,Horst Neve,James Murphy,Jean-Paul Noben,Charles M. A. P. Franz,Christian Cambillau,Jennifer Mahony,Arjen Nauta,Douwe van Sinderen +9 more
TL;DR: It is demonstrated that the above-mentioned three phages possess a complex and atypical baseplate structure and the presence of both RBPs in the tail tip of the mature virion was confirmed, while the anticipated host-binding capabilities of both proteins were also verified.
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