Stephen E. Jones
St Thomas' Hospital
75 Papers
1.1K Citations
Stephen E. Jones is an academic researcher from St Thomas' Hospital. The author has contributed to research in topics: Breast cancer & Exemestane. The author has an hindex of 30, co-authored 75 publications. Previous affiliations of Stephen E. Jones include King's College London.
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Papers
A Randomized Trial Of Exemestane After Two To Three Years Of Tamoxifen Therapy In Postmenopausal Women With Primary Breast Cancer.
R. C. Coombes,Emma Hall,Lorna Gibson,Robert Paridaens,Jacek Jassem,Thierry Delozier,Stephen E. Jones,Isabel Alvarez,Gianfilippo Bertelli,Olaf Ortmann,Alan S. Coates,Emilio Bajetta,D. Dodwell,Robert E. Coleman,Lesley Fallowfield,Elizabeth Mickiewicz,Jens O. Andersen,Per Eystein Lønning,G. Cocconi,Alan L Stewart,N Stuart,Claire Snowdon,M. Carpentieri,Giorgio Massimini,Judith M Bliss +24 more
TL;DR: Exemestane therapy after two to three years ofTamoxifen therapy significantly improved disease-free survival as compared with the standard five years of tamoxIFen treatment.
Association Between Age at Diagnosis and Disease-Specific Mortality Among Postmenopausal Women With Hormone Receptor–Positive Breast Cancer
Willemien van de Water,Christos Markopoulos,Cornelis J.H. van de Velde,Caroline M. Seynaeve,Annette Hasenburg,Daniel Rea,Hein Putter,Johan W.R. Nortier,Anton J. M. de Craen,E. T. M. Hille,Esther Bastiaannet,Peyman Hadji,Rudi G.J. Westendorp,Gerrit-Jan Liefers,Stephen E. Jones +14 more
TL;DR: Among postmenopausal women with hormone receptor-positive breast cancer, increasing age was associated with a higher disease-specific mortality, particularly among patients aged 65 to 74 years.
193
Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study
Sarah Ennis,Catherine Jomary,Robert F. Mullins,Angela J. Cree,Xiaoli Chen,Alex MacLeod,Stephen E. Jones,Andrew Collins,Edwin M. Stone,Edwin M. Stone,Andrew J. Lotery +10 more
TL;DR: A secondary high-density genotyping study across the SERPING1 gene region identified five additional SNP variants similarly associated with age-related macular degeneration that might implicate the classic pathway of complement activation in this disease.
169
Rescue of photoreceptor function by AAV-mediated gene transfer in a mouse model of inherited retinal degeneration
TL;DR: Evidence is provided that rescue of functional photoreceptor neurons can be achieved by somatic gene therapy after the efficacy of a recombinant adeno-associated virus vector to deliver and express the correct form of the cGMP phosphodiesterase-β (PDE-β) gene in the retinas of rd mice.
155
Adjuvant docetaxel and cyclophosphamide plus trastuzumab in patients with HER2-amplified early stage breast cancer: a single-group, open-label, phase 2 study
Stephen E. Jones,Rufus P. Collea,Devchand Paul,Scot Sedlacek,Anne Favret,Ira Gore,Deborah Lindquist,Frankie A. Holmes,Mary Ann K Allison,Barry Don Brooks,Raul M Portillo,Svetislava J. Vukelja,Michael S. Steinberg,Christopher Stokoe,Maria W Crockett,Yunfei Wang,Lina Asmar,Nicholas J. Robert,Joyce O'Shaughnessy +18 more
TL;DR: A short, four-cycle regimen of docetaxel and cyclophosphamide combined with trastuzumab could be an option for adjuvant treatment of women with lower risk HER2-amplified early breast cancer, irrespective of TOP2A status.