Stephanie A. Amici
Ohio State University
26 Papers
68 Citations
Stephanie A. Amici is an academic researcher from Ohio State University. The author has contributed to research in topics: Inflammation & Medicine. The author has an hindex of 12, co-authored 19 publications.
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Papers
Novel Markers to Delineate Murine M1 and M2 Macrophages
Kyle A. Jablonski,Stephanie A. Amici,Lindsay M. Webb,Juan de Dios Ruiz-Rosado,Phillip G. Popovich,Santiago Partida-Sanchez,Mireia Guerau-de-Arellano +6 more
TL;DR: Overall, this work defines exclusive and common M1 and M2 signatures and provides novel and improved tools to distinguish M1 or M2 murine macrophages.
CD38 Is Robustly Induced in Human Macrophages and Monocytes in Inflammatory Conditions.
Stephanie A. Amici,Nicholas A. Young,Janiret Narvaez-Miranda,Kyle A. Jablonski,Jesus Arcos,Lucia E. Rosas,Tracey L. Papenfuss,Jordi B. Torrelles,Wael N. Jarjour,Mireia Guerau-de-Arellano +9 more
TL;DR: It is established that CD38 transcript and protein are robustly induced in human macrophages exposed to LPS (±IFN-γ) inflammatory stimuli, but not with the alternative stimulus, IL-4, which is consistent with an inflammatory marker role for CD38 in human Macrophages and monocytes.
Molecular Mechanisms Modulating the Phenotype of Macrophages and Microglia.
TL;DR: A comprehensive review of the current understanding of how molecular pathways modulate tissue macrophages phenotype is performed, covering both classic pathways and the emerging role of microRNAs, receptor-tyrosine kinases and metabolism in macrophage phenotype.
Control of the Inflammatory Macrophage Transcriptional Signature by miR-155
Kyle A. Jablonski,Andrew D. Gaudet,Stephanie A. Amici,Phillip G. Popovich,Mireia Guerau-de-Arellano +4 more
TL;DR: Data indicate that miR-155 plays an essential role in driving the inflammatory phenotype of M1(LPS+ IFN-γ) macrophages.
QSM is an imaging biomarker for chronic glial activation in multiple sclerosis lesions.
Kelly M. Gillen,Mayyan Mubarak,Calvin Park,Gerald Ponath,Shun Zhang,Alexey Dimov,Maya Levine-Ritterman,Steven Toro,Weiyuan Huang,Stephanie A. Amici,Ulrike W. Kaunzner,Susan A. Gauthier,Mireia Guerau-de-Arellano,Yi Wang,Thanh D. Nguyen,David Pitt +15 more
TL;DR: In this article, human-induced pluripotent stem cell (iPSC)-derived microglia were used to determine the effect of iron on the production of reactive oxygen species (ROS) and pro-inflammatory cytokines.
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