Stéphane St-Onge
Université de Montréal
5 Papers
4 Citations
Stéphane St-Onge is an academic researcher from Université de Montréal. The author has contributed to research in topics: Receptor & Agonist. The author has an hindex of 4, co-authored 5 publications.
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Papers
Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs
Charlotte Avet,Arturo Mancini,Billy Breton,Christian Le Gouill,Alexander S. Hauser,Claire Normand,Hiroyuki Kobayashi,Florence Gross,Mireille Hogue,Viktoriya Lukasheva,Stéphane St-Onge,Marilyn Carrier,Madeleine Héroux,Sandra Morissette,Eric B. Fauman,Jean-Philippe Fortin,Stephan Schann,Xavier Leroy,David E. Gloriam,Michel Bouvier +19 more
TL;DR: In this article, a set of BRET sensors monitoring the activation of the 12 G protein subtypes based on the translocation of their effectors to the plasma membrane (EMTA) was presented.
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Preservation of Post-Infarction Cardiac Structure and Function via Long-Term Oral Formyl Peptide Receptor Agonist Treatment
Ricardo Garcia,Ricardo Garcia,Bruce R. Ito,John A. Lupisella,Nancy A. Carson,Mei-Yin Hsu,Gayani Fernando,Madeleine Héroux,Michel Bouvier,Elizabeth A. Dierks,Ellen K. Kick,David A. Gordon,Jian Chen,Gabe Mintier,Marilyn Carrier,Stéphane St-Onge,Himanshu Shah,Jordan Kelly Towne,Marcela Sotelo Bucardo,Xiuying Ma,Carol S. Ryan,Nicholas R. Wurtz,Jacek Ostrowski,Francisco Villarreal +23 more
TL;DR: In this article, the effects of long-term treatment with compound 43, a small molecule agonist of formyl peptide receptors (FPR1 and FPR2) on macrophages contributes to key cellular activities that can potentiate wound healing.
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β-Adrenergic receptor desensitization in the early stage of hereditary cardiomyopathy in hamsters
TL;DR: Results suggest that the decreased beta-adrenergic-stimulated adenylyl cyclase activity results from a functional uncoupling of the beta AR with no change in receptor density.
4
Recovery of homogeneous and functional beta 2-adrenergic receptors from extracellular baculovirus particles.
Thomas P. Loisel,Hervé Ansanay,Stéphane St-Onge,Pierre Boulanger,Arthur Donny Strosberg,Stefano Marullo,Michel Bouvier +6 more
TL;DR: It is shown that vire particles released from Sf9 cells infected with a recombinant baculovirus coding for the human β2-adrenergic receptor (β2AR) cDNA contain glycosylated and biologically active β2AR.
In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure
Peter S. Gargalovic,Pancras C. Wong,Joelle M. Onorato,Heather Finlay,Tao Wang,Mujing Yan,Earl J. Crain,Stéphane St-Onge,Madeleine Héroux,Michel Bouvier,Carrie Xu,Xue-Qing Chen,Claudia Generaux,Michael R. Lawrence,Ruth R. Wexler,David A. Gordon +15 more
TL;DR: It is shown that oral APJ agonist administration induces a sustained increase in cardiac output in the cardiac disease setting and exhibits a differentiated profile from the renin-angiotensin system inhibitor enalapril, supporting further clinical evaluation of BMS-986224 in heart failure.