Stéphane Pagès

TL;DR: It is demonstrated that rhythmic sensory whisker stimulation efficiently induces synaptic LTP in layer 2/3 pyramidal cells in the absence of somatic spikes, and that whisker stimuli recruit synaptic networks that originate from the posteromedial complex of the thalamus (POm).

TL;DR: Gravity-assisted rehabilitation enabled by the neuromodulation therapy reinforced these reticulospinal projections, rerouting cortical information through this pathway, mediating motor cortex dependent recovery of locomotion in otherwise paralyzed rats.

TL;DR: Interestingly, at early stages of neuronal development in nonpolarized cells, newly formed neurites already contained microtubules of opposite polarity, suggesting that the establishment of uniform plus-end-out micro Tubules occurs during axon formation, a critical process underlying neuronal polarization.

TL;DR: Using a set of complementary behavioral tests, this work provides strong evidence that T. gondii lowers general anxiety in infected mice, increases explorative behaviors, and surprisingly alters predator aversion without selectivity toward felids, and refute the myth of a selective loss of cat fear in T. Gondii-infected mice.