Stephan Patt
University of Jena
51 Papers
503 Citations
Stephan Patt is an academic researcher from University of Jena. The author has contributed to research in topics: Receptor & Glioma. The author has an hindex of 23, co-authored 51 publications. Previous affiliations of Stephan Patt include Max Delbrück Center for Molecular Medicine & Free University of Berlin.
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Papers
Expression of voltage-gated potassium channels Kv1.3 and Kv1.5 in human gliomas.
Katja Preußat,Christian Beetz,Michael Schrey,Robert Kraft,Stefan Wölfl,Rolf Kalff,Stephan Patt +6 more
TL;DR: This study shows a clear differential expression of Kv1.5 in gliomas according to subtype and malignancy grade, which corresponds to previous data on the expression of voltage-gated sodium channels ingliomas, which likewise showed a low or absent expression of channel subtypes in high-grade tumors.
114
Neuron-like physiological properties of cells from human oligodendroglial tumors
Stephan Patt,Stephan Patt,Charalampos Labrakakis,M. Bernstein,Patrick Weydt,Jorge Cervós-Navarro,G. Nisch,Helmut Kettenmann +7 more
TL;DR: The physiological properties of cells in six human oligodendrogliomas and two oligoastrocytomas obtained from surgical material revealed important findings with regard to the origin of these tumors, which implies that oligodendedroglial tumor cells may belong to the neuronal cell lineage.
89
•Journal Article
Pathological changes in dendrites of substantia nigra neurons in Parkinson's disease: a Golgi study.
TL;DR: The findings support the predominant role played by the dopaminergic efferent pathway in the degenerative process in Parkinson's disease and suggest that the substantia nigra lesion is primary in Parkinson’s disease.
83
Cerebral Angiogenesis Triggered By Severe Chronic Hypoxia Displays Regional Differences
TL;DR: The results indicate that the adaptation of the brain circulation to hypoxia is achieved by both angiogenesis and dilatation of microvessels, and that the pattern of the microcirculatory changes is not homogenous in all regions.
68
Action potential-generating cells in human glioblastomas
Charalampos Labrakakis,Stephan Patt,Stephan Patt,Stephan Patt,Patrick Weydt,Jorge Cervós-Navarro,Reinhard Meyer,Helmut Kettenmann +7 more
TL;DR: The findings imply that the tumor tissue can be intrinsically excitable and that neoplastic glial cells themselves may be an etiologic factor for epileptic seizures.