Stephan Erbe
7 Papers
Stephan Erbe is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 2, co-authored 3 publications.
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Papers
Leptin treatment has vasculo-protective effects in lipodystrophic mice
P. Stürzebecher,Susan Kralisch,M. R. Schubert,V. Filipova,Anne Hoffmann,F. Oliveira,B. Sheikh,Matthias Blüher,Alexander Kogel,Markus Scholz,Karoline E. Kokot,Stephan Erbe,Jasmin M Kneuer,Thomas Ebert,Mathias Fasshauer,Konstanze Miehle,Ulrich Laufs,Anke Tönjes,Jes Niels Boeckel +18 more
TL;DR: An important role is identified in controlling endothelial cell function in lipodystrophy syndromes thanks to the effects of leptin on the functional properties of endothelial cells and atherogenesis in lipODYstrophy.
16
Rubella virus infection in endothelial cells reduces angiogenesis via interferon beta-induced CXCL10.
Vivien Henschke,Konstanze Hild,Erik Schilling,Jan Haas,V. Filipova,Stephan Erbe,Roman König,Judith M. Hübschen,Ulrich Laufs,Claudia Claus,Jes Niels Boeckel +10 more
TL;DR: In this paper , the authors identify an important role for antiviral IFN-mediated induction of CXCL10 in the control of EC function during RuV infection and show that RuV-induced transcriptional profile resembled the effects of IFNβ treatment.
2
Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs
Karoline E. Kokot,Jasmin M Kneuer,David John,Sabine Rebs,Maximilian N. Möbius-Winkler,Stephan Erbe,Marion Müller,M. Andritschke,Susanne Gaul,Bilal N. Sheikh,Jan Haas,Holger Thiele,Oliver J. Müller,Susanne Hille,Florian Leuschner,Stefanie Dimmeler,Katrin Streckfuss-Bömeke,Benjamin Meder,Ulrich Laufs,Jes Niels Boeckel +19 more
TL;DR: In this paper , the authors showed that ADAR2 mediates A-to-I RNA editing in failing human heart and showed that the reduction of ADAR 2 increased circRNA levels suggesting a causal effect on increased circRNAs.
The anti-inflammatory LncRNA Heat4 interacts with the pro-inflammatory protein IP1 in non-classical monocytes promoting vascular regeneration
Jasmin M Kneuer,Matthew M. Winkler,Tim Meinecke,Maximilian N. Möbius-Winkler,Ronald Weiss,J. Haas,Aileen Kogel,K.-P. Kresoja,Sebastian Rosch,Stephan Erbe,Karoline E. Kokot,P. Stürzebecher,T. Garfias-Veitl,S. Von Haehling,Tijmen Keller,Holger Thiele,P. Lurz,T Speer,Ulrich Laufs,Jes Niels Boeckel +19 more
TL;DR: This study identifies the lncRNA Heat4 as an anti-inflammatory mediator in non-classical monocytes, promoting vascular regeneration by interacting with the pro-inflammatory protein IP1, and suggests its potential as a novel therapeutic target for cardiovascular diseases.
Abstract P2100: Highly Localized Myocardial Expression Of Brain Natriuretic Peptide In Patients With Mitral Valve Prolapse
Jes Niels Boeckel,Stephan Erbe,Ricardo A. Spampinato,Benjamin Meder,Michael A. Borger,Ulrich Laufs,Maja-Theresa Dieterlen,Daniel Lavall +7 more
TL;DR: Results indicate that mechanical stretch induces highly localized myocardial pathologies with systemic consequences, and spatial transcriptome analysis in MVP patients identifies a transition zone of the INF region of LV which is exposed to high mechanical stretch.