Stefania Cocco
University of Naples Federico II
18 Papers
33 Citations
Stefania Cocco is an academic researcher from University of Naples Federico II. The author has contributed to research in topics: Breast cancer & Medicine. The author has an hindex of 12, co-authored 16 publications.
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Papers
Effects of particulate matter (PM10, PM2.5 and PM1) on the cardiovascular system.
TL;DR: It is here underlined that these adverse health effects depend not only on the level of PM concentration in the air but also on its particular internal composition.
351
Targeting Cell Cycle in Breast Cancer: CDK4/6 Inhibitors
Michela Piezzo,Stefania Cocco,Roberta Caputo,Daniela Cianniello,Germira Di Gioia,Vincenzo Di Lauro,Giuseppina Fusco,Claudia Martinelli,Francesco Nuzzo,Matilde Pensabene,Michelino De Laurentiis +10 more
TL;DR: This review summarizes the available knowledge regarding CDK4/6 inhibitor, the discovery of new biomarkers of response, and the biological rationale for new combination strategies of treatment.
126
Progression-Free Survival and Overall Survival of CDK 4/6 Inhibitors Plus Endocrine Therapy in Metastatic Breast Cancer: A Systematic Review and Meta-Analysis.
Michela Piezzo,Paolo Chiodini,Maria Antonietta Riemma,Stefania Cocco,Roberta Caputo,Daniela Cianniello,Germira Di Gioia,Vincenzo Di Lauro,Francesca Di Rella,Giuseppina Fusco,Giovanni Iodice,Francesco Nuzzo,Carmen Pacilio,Matilde Pensabene,Michelino De Laurentiis +14 more
TL;DR: This meta-analysis of randomized controlled trials (RCTs) is aimed to better characterize the efficacy of CDK4/6 inhibitors in some relevant subgroups and to test heterogeneity between different compounds with a particular focus on their ability to improve overall survival (OS).
NLRP3 as Putative Marker of Ipilimumab-Induced Cardiotoxicity in the Presence of Hyperglycemia in Estrogen-Responsive and Triple-Negative Breast Cancer Cells.
Vincenzo Quagliariello,Michelino De Laurentiis,Stefania Cocco,Giuseppina Rea,Annamaria Bonelli,Antonietta Caronna,Maria Cristina Lombari,Gabriele Conforti,Massimiliano Berretta,Gerardo Botti,Nicola Maurea +10 more
TL;DR: To the authors' knowledge, this is the first evidence that hyperglycemia exacerbates ipilimumab-induced cardiotoxicity and decreases its anticancer efficacy in MCF-7 and MDA-MB-231 cells.
63
Inhibition of autophagy by chloroquine prevents resistance to PI3K/AKT inhibitors and potentiates their antitumor effect in combination with paclitaxel in triple negative breast cancer models
Stefania Cocco,Alessandra Leone,María Roca,Rita Lombardi,Michela Piezzo,Roberta Caputo,Chiara Ciardiello,S. Costantini,Francesca Bruzzese,Maria Josè Sisalli,Alfredo Budillon,Michelino De Laurentiis +11 more
TL;DR: In this article , the authors investigated if two PI3K/AKT inhibitors, i.e., ipatasertib and taselisib, could induce autophagy in breast cancer models, and whether chloroquine (CQ), a well known autoophagy inhibitor, could potentiate the anti-cancer effect in combination with conventional chemotherapy.