Stacy Lee
University of Southern California
9 Papers
47 Citations
Stacy Lee is an academic researcher from University of Southern California. The author has contributed to research in topics: Lytic cycle & Viral replication. The author has an hindex of 7, co-authored 8 publications.
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Papers
When autophagy meets viruses: a double-edged sword with functions in defense and offense
TL;DR: This review discusses recent advances in autophagy studies with respect to virus infection and pathogenesis and suggests that a comprehensive understanding of the roles of Autophagy pathway and autophile genes during viral infection may enable the discovery of novel antiviral drug targets.
Immune evasion by Kaposi's sarcoma-associated herpesvirus.
TL;DR: This article highlights the strategies Kaposi's sarcoma-associated herpesvirus uses to evade, escape and survive its battle against the host's immune system.
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Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 4 (vIRF4) Targets Expression of Cellular IRF4 and the Myc Gene To Facilitate Lytic Replication
Hye-Ra Lee,Sultan Doğanay,Brian Chung,Zsolt Toth,Kevin Brulois,Stacy Lee,Zhansaya Kanketayeva,Pinghui Feng,Taekjip Ha,Jae U. Jung +9 more
TL;DR: Results indicate that the KSHV vIRF4 lytic protein comprehensively targets the expression and function of c- IRF4 to downregulate c-Myc expression, generating a favorable environment for viral lytic replication.
35
Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 4 (vIRF4) Perturbs the G1-S Cell Cycle Progression via Deregulation of the cyclin D1 Gene.
Hye Ra Lee,Jaba Mitra,Stacy Lee,Shou-Jiang Gao,Tae Kwang Oh,Myung Hee Kim,Taekjip Ha,Jae U. Jung +7 more
TL;DR: KSHV vIRF4 targets the β-catenin/CBP cofactor and blocks its occupancy on the cyclin D1 promoter, suppressing the G1-S cell cycle progression and enhancing KSHV replication.
15
New Perspectives on Long COVID Syndrome: The Development of Unusually Delayed and Recurring Pericarditis After a Primary SARS-CoV-2 Infection
TL;DR: This case highlights the importance of recognizing this latent complication of COVID-19 one year after the initial infection and how the symptoms can persist beyond the one-year period.