Spenser S. Smith
University of California, San Francisco
10 Papers
12 Citations
Spenser S. Smith is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Osteoblast & Biology. The author has an hindex of 5, co-authored 10 publications. Previous affiliations of Spenser S. Smith include College of Idaho & University of Connecticut Health Center.
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Papers
Cadmium-induced decrease in RUNX2 mRNA expression and recovery by the antioxidant N-acetylcysteine (NAC) in the human osteoblast-like cell line, Saos-2.
Spenser S. Smith,Jackeline Rodriguez Reyes,Kate S. Arbon,Wendy A. Harvey,Lindsey M. Hunt,Sara J. Heggland +5 more
TL;DR: It is hypothesized that cadmium exposure induces oxidative stress which leads to decreased RUNX2 mRNA expression and increased apoptotic death, and predicted that the antioxidant NAC mitigates the damaging effects of cadmiam.
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miR-433-3p Suppresses Bone Formation and mRNAs Critical for Osteoblast Function in Mice
John Garcia,Spenser S. Smith,Sangita Karki,Hicham Drissi,Henry H. Hrdlicka,Daniel W. Youngstrom,Anne M. Delany +6 more
TL;DR: In this article, the authors showed that miR-433-3p is progressively decreased during osteoblastic differentiation of primary mouse bone marrow stromal cells in vitro, and confirm its negative regulation of this process.
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Variations in hepatic biomarkers in American alligators ( Alligator mississippiensis ) from three sites in Florida, USA
Mark P. Gunderson,Melissa A. Pickett,Justin T. Martin,Elizabeth J. Hulse,Spenser S. Smith,Levi A. Smith,Rachel M. Campbell,Russell H. Lowers,Ashley S.P. Boggs,Louis J. Guillette +9 more
TL;DR: It is concluded that GST and MT demonstrate age and sex specific patterns in the alligators inhabiting these study sites and that the observed variation among sites could be due to differences in contaminant exposure.
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Stable integration of an optimized inducible promoter system enables spatiotemporal control of gene expression throughout avian development.
TL;DR: A novel, sensitive, tunable, and stable inducible-promoter system for high-resolution gene manipulation in vivo to control the timing, spatial domains, and levels of gene misexpression throughout avian development.
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Stable integration of an optimized inducible promoter system enables spatiotemporal control of gene expression throughout avian development
TL;DR: A novel, sensitive, tunable, and stable inducible-promoter system for high-resolution gene manipulation in vivo that produces robust transgene expression in the presence of doxycycline at any point during embryonic development in ovo or in culture.