Sovitj Pou
University of Maryland, Baltimore
51 Papers
775 Citations
Sovitj Pou is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Spin trapping & Hydroxyl radical. The author has an hindex of 22, co-authored 45 publications. Previous affiliations of Sovitj Pou include Duke University & University of Maryland Biotechnology Institute.
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Papers
Oxygen Reduction by Nitric-oxide Synthases*
TL;DR: The electron transport chain of NOS is examined with special emphasis on O2 production and these findings are interpreted with a view toward NOS structure-function and the kinetics of the electron transfer reactions.
419
Spin trapping evidence for myeloperoxidase-dependent hydroxyl radical formation by human neutrophils and monocytes.
TL;DR: The ability of human neutrophils and monocytes to generate hydroxyl radical through a myeloperoxidase-dependent mechanism is supported.
242
Mechanism of superoxide generation by neuronal nitric-oxide synthase.
TL;DR: It is shown that NOS I generates O·̄2 and the formation of this free radical occurs at the heme domain, and of interest was the finding that the frequently used NOS inhibitor N G-monomethyll-arginine enhanced O·⋅ production in the presence of l- arginine because this antagonist attenuated NO⊅formation.
198
Problems associated with spin trapping oxygen-centered free radicals in biological systems.
Sovitj Pou,Daniel J. Hassett,Daniel J. Hassett,Bradley E. Britigan,Bradley E. Britigan,Myron S. Cohen,Myron S. Cohen,Gerald M. Rosen,Gerald M. Rosen +8 more
TL;DR: Plusieurs solutions sont proposees pour remedier aux differents problemes rencontres par l'utilisation de nitrones tels que l'oxyde-1 pyrolline-1 dimethyl 5,5 qui reagit avec des radicaux libres de courte duree de vie pour donner un nitroxyde.
151
A Kinetic Approach to the Selection of a Sensitive Spin Trapping System for the Detection of Hydroxyl Radical
Sovitj Pou,Carroll L. Ramos,T. Gladwell,E. Renks,M. Centra,D. Young,Myron S. Cohen,Gerald M. Rosen,Gerald M. Rosen +8 more
TL;DR: The efficiency of spin trapping and the marked stability of the resulting spin-trapped adduct confer a high degree of sensitivity and demonstrate the potential application of 4-POBN/ETOH toward the detection of hydroxyl radical in biological systems.
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