Sonja Löfmark
Karolinska University Hospital
11 Papers
79 Citations
Sonja Löfmark is an academic researcher from Karolinska University Hospital. The author has contributed to research in topics: Drug resistance & Clindamycin. The author has an hindex of 9, co-authored 10 publications. Previous affiliations of Sonja Löfmark include Karolinska Institutet.
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Papers
Long-term ecological impacts of antibiotic administration on the human intestinal microbiota
TL;DR: It is demonstrated that long after the selection pressure from a short antibiotic exposure has been removed, there are still persistent long term impacts on the human intestinal microbiota that remain for up to 2 years post-treatment.
Metronidazole Is Still the Drug of Choice for Treatment of Anaerobic Infections
TL;DR: Metronidazole is still the criterion standard for therapy of anaerobic infections, as was described by Tally and colleagues 35 years ago and is considered to be a cost-effective drug because of its low cost, good activity against pathogenicAnaerobic bacteria, favorable pharmacokinetic and pharmacodynamic properties, and minor adverse effects.
Clindamycin-induced enrichment and long-term persistence of resistant Bacteroides spp. and resistance genes
Sonja Löfmark,Cecilia Jernberg,Cecilia Jernberg,Janet K. Jansson,Charlotta Edlund,Charlotta Edlund +5 more
TL;DR: The results indicate that even a short-term antibiotic administration can cause long-term alterations in the commensal microbiota of individual subjects, detectable 2 years after dosing.
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Inducible Metronidazole Resistance and nim Genes in Clinical Bacteroides fragilis Group Isolates
TL;DR: Nitroimidazole resistance genes were detected in 2% of clinical Bacteroidesfragilis group strains isolated from 19 European countries, and a novel nim gene was identified, which emphasizes the importance of acknowledging metronidazoles resistance in the clinical setting.
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Genetic basis of resistance in Propionibacterium acnes strains isolated from diverse types of infection in different European countries.
TL;DR: Of 36 P. acnes isolates tested, none was found to carry the erm(X) resistance gene and no correlation was noticed between different resistance genotypes of CL and EM resistant strains and pulsed-field types.
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