Sol Bobst
Shell Oil Company
6 Papers
Sol Bobst is an academic researcher from Shell Oil Company. The author has contributed to research in topics: Reference dose & Applicability domain. The author has an hindex of 4, co-authored 6 publications.
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Papers
Skin sensitization in silico protocol
Candice Y. Johnson,Ernst Ahlberg,Lennart T. Anger,Lisa Beilke,Romualdo Benigni,Joel P. Bercu,Sol Bobst,David Bower,Alessandro Brigo,Sarah Campbell,Mark T. D. Cronin,Ian Crooks,Kevin P. Cross,Tatyana Y. Doktorova,Thomas Exner,David Faulkner,Ian M. Fearon,Markus Fehr,Shayne C. Gad,Véronique Gervais,Amanda Giddings,Susanne Glowienke,Barry Hardy,Catrin Hasselgren,Jedd Hillegass,Robert A. Jolly,Eckart Krupp,Liat Lomnitski,Jason Magby,Jordi Mestres,Lawrence Milchak,Scott Miller,Wolfgang Muster,Louise Neilson,Rahul Parakhia,Alexis Parenty,Patricia Parris,Alexandre Paulino,Ana Theresa Paulino,David W. Roberts,Harald Schlecker,Reinhard Stidl,Diana Suarez-Rodrigez,David T. Szabo,Raymond R. Tice,Daniel Urbisch,Anna Vuorinen,Brian A. Wall,Thibaud Weiler,Angela White,Jessica Whritenour,Joerg Wichard,David Woolley,Craig Zwickl,Glenn J. Myatt +54 more
TL;DR: Based on the relevance of the mechanisms and effects as well as the strengths and limitations of the experimental systems used to identify them, rules and principles are defined for deriving skin sensitization in silico assessments.
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Case Studies Chapter
Sol Bobst,Jose A. Torres,Rhian B. Cope +2 more
- 01 Jan 2015
TL;DR: This chapter provides four hypothetical case study examples of risk assessment as they apply to (1) policy, (2) development of a reference dose concentration, (3) exposure assessment and (4) analysis of a parasiticide case study.
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Oral Reference Dose for ethylene glycol based on oxalate crystal-induced renal tubule degeneration as the critical effect
TL;DR: Pertinent in vitro and in vivo studies related to one of these metabolites, calcium oxalate, and its role in crystal-induced nephropathy are summarized, and the weight of evidence to establish the mode of action for renal toxicity is reviewed.
Performance evaluation of CAESAR–QSAR output using PAHs as a case study
Marjan Vračko,Sol Bobst +1 more
TL;DR: In this article, the set of 16 polycyclic aromatic hydrocarbon compounds was examined with the Internet available quantitative structure-activity relationship (QSAR) CAESAR models, which included the predicted classifications, the analysis of applicability domains, and the similarity sets, which consist of the similar compounds from the training sets.
Toxicological Risk Assessment for Beginners
Jose A. Torres,Sol Bobst +1 more
- 22 Dec 2015
TL;DR: Toxicological risk assessment for beginners /, Toxicological risk Assessment for beginners for beginners, and more information is provided.