Sofie Vande Casteele
Ghent University
12 Papers
187 Citations
Sofie Vande Casteele is an academic researcher from Ghent University. The author has contributed to research in topics: Mass spectrometry & Tandem mass spectrometry. The author has an hindex of 8, co-authored 12 publications.
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Papers
Dissection of the phytohormonal regulation of trichome formation and biosynthesis of the antimalarial compound artemisinin in Artemisia annua plants
Lies Maes,Filip Van Nieuwerburgh,Yansheng Zhang,Darwin W. Reed,Jacob Pollier,Sofie Vande Casteele,Dirk Inzé,Patrick S. Covello,Dieter Deforce,Alain Goossens +9 more
TL;DR: Analysis of phytohormone-modulated transcriptional regulons provides clues to dissect the concerted regulation of metabolism and development of plant trichomes.
Quantitation of artemisinin and its biosynthetic precursors in Artemisia annua L. by high performance liquid chromatography-electrospray quadrupole time-of-flight tandem mass spectrometry.
Filip Van Nieuwerburgh,Sofie Vande Casteele,Lies Maes,Alain Goossens,Dirk Inzé,Jan Van Bocxlaer,Dieter Deforce +6 more
TL;DR: This study reports the development and validation of a rapid, sensitive and selective assay for the quantitation of artemisinin, arteannuin B, artemisitene and artemisinic acid in Artemisia annua L. by reversed phase high performance liquid chromatography (HPLC) electrospray (ESI) quadrupole time of flight (Q-TOF) tandem mass spectrometry (MS/MS).
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Removing the Hidden Data Dependency of DIA with Predicted Spectral Libraries.
Bart Van Puyvelde,Sander Willems,Ralf Gabriels,Simon Daled,Laura De Clerck,Sofie Vande Casteele,An Staes,Francis Impens,Dieter Deforce,Lennart Martens,Sven Degroeve,Maarten Dhaenens +11 more
TL;DR: DIA can be redeemed from this dependency by combining predicted fragment intensities and retention times with narrow window DIA, eliminating variation in library building and omits stochastic sampling, finally making the DIA workflow fully deterministic.
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Confirmation of the identity of residues using quadrupole time-of-flight mass spectrometry
TL;DR: In this paper, the authors used a triple quadrupole and a time-of-flight mass analyser (Q-TOF) for residue analysis, compared to the more common triple quad-rupole instruments.
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Exact mass measurement of product ions for the structural confirmation and identification of unknown compounds using a quadrupole time-of-flight spectrometer: a simplified approach using combined tandem mass spectrometric functions.
Karine M. Clauwaert,Sofie Vande Casteele,Bart A. Sinnaeve,Dieter Deforce,Willy E. Lambert,Carlos Van Peteghem,Jan Van Bocxlaer +6 more
TL;DR: A simple method to perform lock mass corrected accurate mass measurements in tandemmass spectrometry (MS/MS) with a quadrupole time-of-flight (Q-TOF) mass spectrometer is described.
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