Sofia K. Forslund
Max Delbrück Center for Molecular Medicine
90 Papers
71 Citations
Sofia K. Forslund is an academic researcher from Max Delbrück Center for Molecular Medicine. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 14, co-authored 35 publications. Previous affiliations of Sofia K. Forslund include Charité.
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Papers
eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated orthology resource based on 5090 organisms and 2502 viruses.
Jaime Huerta-Cepas,Damian Szklarczyk,Davide Heller,Ana Hernández-Plaza,Sofia K. Forslund,Helen Cook,Daniel R. Mende,Ivica Letunic,Thomas Rattei,Lars Juhl Jensen,Christian von Mering,Peer Bork +11 more
TL;DR: eggNOG as discussed by the authors is a public database of orthology relationships, gene evolutionary histories and functional annotations, with a major update of the underlying genome sets, which have been expanded to 4445 representative bacteria and 168 archaea derived from 25 038 genomes.
Structure and function of the global topsoil microbiome.
Mohammad Bahram,Mohammad Bahram,Mohammad Bahram,Falk Hildebrand,Sofia K. Forslund,Sofia K. Forslund,Jennifer L. Anderson,Nadejda A. Soudzilovskaia,Peter M. Van Bodegom,Johan Bengtsson-Palme,Sten Anslan,Sten Anslan,Luis Pedro Coelho,Helery Harend,Jaime Huerta-Cepas,Marnix H. Medema,Mia R. Maltz,Sunil Mundra,Pål Axel Olsson,Mari Pent,Sergei Põlme,Shinichi Sunagawa,Martin Ryberg,Leho Tedersoo,Peer Bork,Peer Bork +25 more
TL;DR: It is shown that bacterial, but not fungal, genetic diversity is highest in temperate habitats and that microbial gene composition varies more strongly with environmental variables than with geographic distance, and that the relative contributions of these microorganisms to global nutrient cycling varies spatially.
Recovery of gut microbiota of healthy adults following antibiotic exposure
Albert Pallejà,Kristian Hallundbæk Mikkelsen,Sofia K. Forslund,Alireza Kashani,Kristine H. Allin,Kristine H. Allin,Trine Nielsen,Tue H. Hansen,Suisha Liang,Qiang Feng,Chenchen Zhang,Paul Theodor Pyl,Luis Pedro Coelho,Huanming Yang,Jian Wang,Athanasios Typas,Morten Frost Munk Nielsen,Henrik Nielsen,Peer Bork,Jun Wang,Tina Vilsbøll,Torben Hansen,Torben Hansen,Filip K. Knop,Manimozhiyan Arumugam,Oluf Pedersen +25 more
TL;DR: It is shown that the human gut microbiome can recover after a clinically relevant, broad-spectrum antibiotic treatment and characterization of the resistome indicates that antibiotic resistance genes can impact the recovery process.
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Short-Chain Fatty Acid Propionate Protects From Hypertensive Cardiovascular Damage
Hendrik Bartolomaeus,András Balogh,Mina Yakoub,Susanne Homann,Lajos Markó,Sascha Höges,D. Tsvetkov,D. Tsvetkov,D. Tsvetkov,Alexander Krannich,Sebastian Wundersitz,Sebastian Wundersitz,Ellen G. Avery,Nadine Haase,Kristin Kräker,Lydia Hering,Martina Maase,Kristina Kusche-Vihrog,Maria Grandoch,Jens Fielitz,Stefan Kempa,Maik Gollasch,Maik Gollasch,Zhaxybay Zhumadilov,Samat Kozhakhmetov,Almagul Kushugulova,Kai-Uwe Eckardt,Ralf Dechend,Lars Christian Rump,Sofia K. Forslund,Dominik N. Müller,Johannes Stegbauer,Nicola Wilck +32 more
TL;DR: The data suggest that lifestyle modifications leading to augmented SCFA production could be a beneficial nonpharmacological preventive strategy for patients with hypertensive cardiovascular disease and emphasize an immune-modulatory role of SCFAs and their importance for cardiovascular health.
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Propionic Acid Shapes the Multiple Sclerosis Disease Course by an Immunomodulatory Mechanism
Alexander Duscha,Barbara Gisevius,Sarah Hirschberg,Nissan Yissachar,Gabriele I. Stangl,Eva Eilers,Eva Eilers,Verian Bader,Stefanie Haase,Johannes Kaisler,Christina David,Ruth Schneider,Riccardo Troisi,Daniel Zent,Tobias Hegelmaier,Nikolaos Dokalis,Sara Gerstein,Sara Del Mare-Roumani,Sivan Amidror,Ori Staszewski,Gereon Poschmann,Kai Stühler,Frank Hirche,András Balogh,Stefan Kempa,Pascal Träger,Mario M. Zaiss,Jacob Bak Holm,Megan G. Massa,Henrik Nielsen,Andreas Faissner,Carsten Lukas,Sören Gatermann,Markus Scholz,Horst Przuntek,Marco Prinz,Sofia K. Forslund,Konstanze F. Winklhofer,Dominik N. Müller,Ralf A. Linker,Ralf Gold,Aiden Haghikia +41 more
TL;DR: It is suggested that PA can serve as a potent immunomodulatory supplement to MS drugs and as an add-on to MS immunotherapy.
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