Sofia-Iris Bibli
Goethe University Frankfurt
23 Papers
80 Citations
Sofia-Iris Bibli is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Ischemia & Enos. The author has an hindex of 12, co-authored 22 publications. Previous affiliations of Sofia-Iris Bibli include National and Kapodistrian University of Athens.
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Papers
Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction
Lukas Tombor,David John,Simone F. Glaser,Guillermo Luxán,Elvira Forte,Milena B. Furtado,Nadia A. Rosenthal,Nina Baumgarten,Marcel H. Schulz,Janina Wittig,Eva-Maria Rogg,Yosif Manavski,Ariane Fischer,Marion Muhly-Reinholz,Kathrin Klee,Mario Looso,Carmen Selignow,Till Acker,Sofia-Iris Bibli,Ingrid Fleming,Ralph Patrick,Ralph Patrick,Richard P. Harvey,Richard P. Harvey,Wesley Abplanalp,Stefanie Dimmeler +25 more
TL;DR: In this paper, the authors explore the kinetics and individual cellular responses of endothelial cells after myocardial infarction by using single cell RNA sequencing and demonstrate a time dependent switch in endothelial cell proliferation and inflammation associated with transient changes in metabolic gene signatures.
Comparison of the effects of e-cigarette vapor with cigarette smoke on lung function and inflammation in mice
Constantinos Glynos,Sofia-Iris Bibli,Sofia-Iris Bibli,Paraskevi Katsaounou,Athanasia Pavlidou,Christina Magkou,Vassiliki Karavana,Stavros Topouzis,Ioannis Kalomenidis,Spyros Zakynthinos,Andreas Papapetropoulos +10 more
TL;DR: Exposure to e-cig vapor can trigger inflammatory responses and adversely affect respiratory system mechanics and it is concluded that both e- cig vaping and conventional cigarette smoking negatively impact lung biology.
Oleuropein prevents doxorubicin-induced cardiomyopathy interfering with signaling molecules and cardiomyocyte metabolism
Ioanna Andreadou,Emmanuel Mikros,Konstantinos Ioannidis,Fragiska Sigala,Katerina K. Naka,Sarantos Kostidis,Dimitrios Farmakis,Roxane Tenta,Nikolaos Kavantzas,Sofia-Iris Bibli,Evangelos Gikas,Leandros Skaltsounis,Dimitrios Th. Kremastinos,Efstathios K. Iliodromitis +13 more
TL;DR: Activation of AMPK and suppression of iNOS by oleuropein seem to prevent the structural, functional and histopathological cardiac effects of chronic DXR toxicity.
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Coronary Revascularization During Heart Regeneration Is Regulated by Epicardial and Endocardial Cues and Forms a Scaffold for Cardiomyocyte Repopulation.
Rubén Marín-Juez,Hadil El-Sammak,Christian S. M. Helker,Aosa Kamezaki,Sri Teja Mullapuli,Sofia-Iris Bibli,Matthew J. Foglia,Ingrid Fleming,Kenneth D. Poss,Didier Y.R. Stainier +9 more
TL;DR: It is shown that revascularization requires a coordinated multi-tissue response culminating with the formation of a complex vascular network available as a scaffold for cardiomyocyte repopulation.
113
Mapping the Endothelial Cell S-Sulfhydrome Highlights the Crucial Role of Integrin Sulfhydration in Vascular Function
Sofia-Iris Bibli,Jiong Hu,Mario Looso,Andreas Weigert,Corina Ratiu,Janina Wittig,Maria Kyriaki Drekolia,Lukas Tombor,Voahanginirina Randriamboavonjy,Matthias S. Leisegang,Philipp Goymann,Fredy Delgado Lagos,Beate Fisslthaler,Sven Zukunft,Anastasia Kyselova,Alberto Fernando Oliveira Justo,Juliana Heidler,Diamantis I. Tsilimigras,Ralf P. Brandes,Stefanie Dimmeler,Andreas Papapetropoulos,Andreas Papapetropoulos,Stefan Knapp,Stefan Offermanns,Ilka Wittig,Stephen L. Nishimura,Fragiska Sigala,Ingrid Fleming +27 more
TL;DR: Vascular disease is associated with marked changes in the S-sulfhydration of endothelial cell proteins involved in mediating responses to flow, and short term H2Sn supplementation improved vascular reactivity in humans highlighting the potential of interfering with this pathway to treat vascular disease.
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