than bacteria are not covered. There is also a large amount of practical information on the purification, electron microscopy, and restriction mapping of plasmid DNA, and on the use of plasmids in gene cloning and sequencing. Transposable elements are covered also. This book does not appear to be aimed specifically at one group of scientists. From the point of view of readers of the Journal of Medical Genetics, the lack of a chapter on the medical significance of plasmids-for example, their role in the spread of antibiotic resistance-is disappointing. Readers who are interested in the genetic engineering applications will find much of interest, but would probably do better with one of the more specialised texts on this subject. Therefore, the book seems to fall between two or three stools. The presentation and style of the book are both good, with plenty of figures, tables, and references. The practical procedures are generally described in enough detail to be useful. Overall, although all of the individual articles are worthwhile, the book as a whole does not have an obvious appeal.

https://jmg.bmj.com/content/jmedgenet/22/6/503.2.full.pdf

Ectodermal dysplasias: a clinical and genetic study.

Chapter-10 Cysts and Tumors of Odontogenic Origin

The increasing demands for the management of hemostasis and tissue sealing drive the development of novel bioadhesives, which can overcome the disadvantages of conventional sutures such as additional tissue damage, increased infection probability, and body fluid/air leakage. Bioadhesives can form a protective layer with seamless adhesion between the injured tissues, thereby quickly closing the wound and creating appropriate microenvironments for wound healing. In this review, the recent advancement in bioadhesives made of natural macromolecules (polysaccharides and proteins, etc.) and synthetic macromolecules (cyanoacrylate, polyethylene glycol, polyurethane, etc.) have been summarized. The gelation and adhesion mechanisms that determine the bioadhesive properties and sealing functions are highlighted, and the current clinical applications of bioadhesives are also discussed. Based on these findings, a brief outlook on the future of bioadhesive is explored.

Recent progress in surgical adhesives for biomedical applications

Postoperative pain and its management.

The aim of this study was to evaluate the value of MRI in the prenatal diagnosis and classification of cleft palate (CP). We collected 94 fetal cases that were suspected of cleft palate with or without cleft lip by prenatal ultrasound (US) and then carried out further MRI to examine the entire body of each fetus within 1 week. The diagnoses resulting from MRI and US examination were compared separately with the final diagnoses obtained from postnatal physical examination or fetal autopsy. The diagnostic accuracy between MRI and US was then determined. During the follow-up period, the results for 6 fetuses (6.38%) were lost. Of the remaining 88 cases, the final diagnoses identified 23 cases of cleft lip (CL), 45 cases of unilateral cleft lip with cleft palate (UCLP), 4 cases of median cleft lip with cleft palate (MCLP), 12 cases of bilateral cleft lip with cleft palate (BCLP), 3 cases of unilateral cleft lip and cleft alveolus (CLA), and 1 case of isolated cleft palate (CPO). The total accuracy rate of US was 59.09%, while that of MRI was 92.05%. More importantly, 81 cases were accurately identified by MRI; the accuracy rate for CL, UCLP, MCLP, BCLP, CLA, and CPO was 86.96%, 95.56%, 100%, 91.67%, 66.67%, and 100%, respectively. Our results suggest that MRI could be a useful adjunct to US examination in the prenatal diagnosis of fetuses with cleft palate, and further demonstrates the classification and degree of involvement of the cleft palate. • MRI is a useful adjunct to prenatal ultrasound.
 • MRI has a higher accuracy rate for CP.
 • The accurate classification of CP diagnosed by MRI can guide clinical management.

The prenatal diagnosis and classification of cleft palate: the role and value of magnetic resonance imaging

Objectives Wound closure is a part of any surgical procedure. Wound care and healing process are concepts, which are usually reliant upon sutures. The suture and non-suture repair of the tissues has been a major concern to surgeons for over four thousand years. The objective of this study is to compare the rates of infection, wound dehiscence, necrosis and time required by N-butyl cyanoacrylate tissue adhesive and nylon sutures in extraoral maxillofacial wound closer. Materials and methods 24 patients requiring external wound closing were included in this study. Patients were divided in two groups, in one group wound closer was done by N-butyl cyanoacrylate tissue adhesive and by conventional nylon suture in the other group. The software STATA® of StataCorp was used in statistical analysis if this study. Results Wound infection, dehiscence, necrosis of tissue edges, time taken for closure was much less in case of tissue adhesive than conventional sutures. Conclusion Advantages of tissue adhesives over conventional wound closure techniques include easy to use, excellent bacteriostatic property, decreased repair time, elimination of recall visits and comparable short and long-term cosmetic outcome. Though tissue adhesives have many advantages over conventional wound closure techniques, they can be used as an alternative to sutures only in superficial small and tension free skin incisions or lacerations.

Comparison between N-butyl cyanoacrylate tissue adhesive and Ethilon nylon sutures in extraoral maxillofacial incisions: A randomized prospective study

Odontogenic tumors develop in the jaws from odontogenic tissues such as enamel organ, Hertwig epithelial root sheath, dental lamina, and so on. A variety of tumors unique to the maxilla and mandible are therefore seen. Calcifying epithelial odontogenic tumor (CEOT) is a rare, aggressive, benign odontogenic tumor of epithelial origin accounting for only about 1% of all odontogenic tumors. It is eponymously called “Pindborg tumor”, as it was first described by Pindborg in 1955. The origin of this locally invasive tumor remains unknown. It is thought to arise from stratum intermedium. It commonly affects the posterior mandible manifesting as a slow-growing asymptomatic swelling often associated with an impacted tooth. We report a case of CEOT, for which, owing to its huge size we have proposed the term “giant” Pindborg tumor (CEOT). This is probably the largest case of this tumor reported so far in the English literature. The present case also has the classic yet rare “driven snow” appearance of the tumor on radiographs.

Giant pindborg tumor (calcifying epithelial odontogenic tumor): an unusual case report with radiologic-pathologic correlation

Diffuse large B-cell lymphomas (DLBCLs) are defined as neoplasms of large transformed B cells, i.e. with nuclear diameter more than twice that of a normal lymphocyte. These account for 30-40% of all adult non-Hodgkin's lymphomas (NHL). Intraoral lymphomas are relatively rare and often difficult to diagnose in clinical settings. In this case report, we describe a case of primary DLBCL affecting the anterior part of the hard palate of an elderly male patient. DLBCL of anterior part of hard palate is yet to be reported in the English literature, even though DLBCL cases involving the posterior palate have been recorded, thus making the present case to be first of its kind. Emphasis has also been given on the subclassification, differential diagnosis and prognostic antibody factors determining the outcome of DLBCL.

Primary diffuse large B-cell lymphoma in the anterior hard palate: A rare case report with review of literature.

Comparative analysis between direct Conventional Mandibular nerve block and Vazirani-Akinosi closed mouth Mandibular nerve block technique

Ectrodactyly‐ectodermic dysplasia‐cleft lip/palate (EEC) syndrome is a rare congenital anomaly of inherited origin and varying clinical features. This syndrome has three main symptoms, which display variable expression and penetrance. The management of this syndrome is challenging, with few reports in the medical literature. We present a case of a 22‐year‐old boy with EEC syndrome and offer insight into current knowledge about this syndrome.

/pdf/ectrodactyly-ectodermal-dysplasia-cleft-lip-palate-syndrome-1k4wm1mutr.pdf

Ectrodactyly - ectodermal dysplasia - cleft lip/palate syndrome: a rare entity

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