Pelvic organ prolapse and vaginal cancer: A systematic literature review

A new continuous distribution called the extended odd Weibull power Lomax (ExOW-POLO) distribution is introduced and studied. Numerous reliability and statistical features are derived. Additionally studied are point estimates using maximum likelihood, maximum product space, least square, weighted least square, and Bayesian estimation techniques. The mean square error and bias of the maximum likelihood and Bayesian parameter estimators are computed using simulation approaches, such as Markov chain Monte Carlo. Two intraocular pressure (IOP) real datasets were conducted between January 2015 and February 2018 on 49 patients (84 eyes) under the age of two who presented with primary congenital glaucoma to the Paediatric Ophthalmology Unit of the Mansoura Ophthalmic Center of Mansoura University in Egypt have been fitted the ExOW-POLO distribution. Comparing the properties of the proposed distribution’s fitting of the data to recognized extensions of the Lomax distribution. The analysis revealed that the most well-known extensions of Lomax distribution were made by the ExOW-POLO distribution outfit. In addition, the correlation measures and independent sample test for the two IOP real datasets are introduced with (A) Levene’s test for equality of variances for the two cases and (B) the t-test for equality of means. For Levene’s test for equality of variances: the null hypothesis is that equal variances are assumed and the alternative hypothesis is that equal variances are not assumed.

Classical and Bayesian estimation for the extended odd Weibull power Lomax model with applications

Abstract Background Synovial sarcoma is a malignant tumor that constitutes up to 10% of all soft-tissue sarcomas. The most frequent metastatic sites of synovial sarcoma are the lungs, lymph nodes, and bone, whereas pancreatic metastasis is extremely rare. Here, we report a case of pancreatic metastasis of synovial sarcoma. Case presentation Nine years before presentation, a 31-year-old woman underwent extensive resection of the primary tumor after chemotherapy for left upper extremity synovial sarcoma. Six months before presentation, interscapulothoracic amputation was performed for an enlarged mass in the left upper extremity; the patient was treated with pazopanib. Three months before presentation, chest computed tomography showed multiple lung metastases; during subsequent follow-up, abdominal computed tomography revealed a pancreatic metastasis of synovial sarcoma. The doubling time of the pancreatic tumor was 14 days, and it grew rapidly. Furthermore, treatment-resistant pancreatitis symptoms were detected; thus, we performed distal pancreatectomy and administered one course of a 70% dose of trabectedin. However, the patient died of rapid progression of lung metastasis and respiratory failure within 2 months after surgery. Conclusions Pancreatectomy may be carefully performed in cases of isolated pancreatic metastasis. However, the presence of other distant extrapancreatic metastases (e.g., uncontrolled lung metastases) may rule out pancreatectomy treatment. 

/pdf/early-progression-of-a-pancreatic-metastasis-of-synovial-fchghl1v.pdf

Early progression of a pancreatic metastasis of synovial sarcoma after pancreatectomy

Primary or secondary clear cell sarcoma of the pancreas is an exceedingly rare and aggressive disease. In addition to pathology, molecular analysis is pivotal in differential diagnosis, especially with malignant melanoma. A key aspect in identifying clear cell sarcoma is specific genetic alterations, notably the translocation of t(12;22) (q13;q13), a diagnostic hallmark of this sarcoma subtype, which is absent in malignant melanoma. Treatment of primary clear cell sarcoma of the pancreas is the same as that for adenocarcinoma. 

Metastatic clear cell sarcoma of the pancreas: A sporadic cancer

Synovial sarcoma usually presents in the lower extremities and metastasizes to the lungs; however, unusual patterns of recurrence can occur. For patients with recurrent synovial sarcoma to a proximal peripancreatic lymph node, a pancreaticoduodenectomy or Whipple procedure is the best option for a cure. Lymph node metastasis from synovial sarcoma is exceptionally rare, and data guiding the use of the Whipple procedure for curative resection of metastatic synovial sarcoma are even more sparse. In this report, we describe the management of a patient with metastatic synovial sarcoma to a proximal peripancreatic lymph node with a pancreaticoduodenectomy.

/pdf/first-recurrence-of-synovial-sarcoma-presenting-with-8bw3umen.pdf

First Recurrence of Synovial Sarcoma Presenting With Solitary Pancreatic Mass

Pancreatic metastases are rare, accounting for 2%–3% of pancreatic tumors. The pancreas represents an unusual metastatic site of synovial sarcoma (SS) outside the usual localizations (regional node...

https://journals.sagepub.com/doi/pdf/10.1177/2036361320983691

The management of pancreatic metastasis from synovial sarcoma of the soft tissue: A case report.

Warty squamous cell carcinoma (WSCC), is a rare variant of squamous cell carcinoma that occurs mostly in younger women, but can occur in old women. It is due to human papillomavirus (HPV) infection...

https://journals.sagepub.com/doi/pdf/10.1177/11795476211011206

Aggressive Behavior of Warty Squamous Cell Carcinoma of the Vagina Associated with Uterine Prolapsed: Unusual Report.

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The management of pancreatic metastasis from synovial sarcoma of the soft tissue: A case report.

Aggressive Behavior of Warty Squamous Cell Carcinoma of the Vagina Associated with Uterine Prolapsed: Unusual Report.