Skylar Carlson
University of Illinois at Chicago
6 Papers
25 Citations
Skylar Carlson is an academic researcher from University of Illinois at Chicago. The author has contributed to research in topics: Quorum sensing & Mode of action. The author has an hindex of 4, co-authored 6 publications. Previous affiliations of Skylar Carlson include University of the Pacific (United States).
Chat about Author
Papers
Tools for Characterizing Bacterial Protein Synthesis Inhibitors
Cédric Orelle,Skylar Carlson,Bindiya Kaushal,Mashal M. Almutairi,Haipeng Liu,Anna Ochabowicz,Selwyn Quan,Van Cuong Pham,Catherine L. Squires,Brian T. Murphy,Alexander S. Mankin +10 more
TL;DR: A two-pronged approach for the characterization of inhibitors of protein synthesis (ChIPS) that can be performed within a few days and provide a rapid and efficient approach for identifying the site and mode of action of translation inhibitors targeting the bacterial ribosome.
114
Diaza-anthracene Antibiotics from a Freshwater-Derived Actinomycete with Selective Antibacterial Activity toward Mycobacterium tuberculosis
Michael W. Mullowney,CH Hwang,Andrew G. Newsome,Xiaomei Wei,Urszula Tanouye,Baojie Wan,Skylar Carlson,Nanthida Joy Barranis,Eoghainín Ó hAinmhire,Wei Lun Chen,Kalyanaraman Krishnamoorthy,John H. White,Rachel Blair,Hyunwoo Lee,Joanna E. Burdette,Pradipsinh K. Rathod,Tanya Parish,Sang-Hyun Cho,Scott G. Franzblau,Brian T. Murphy +19 more
TL;DR: This study establishes freshwater environments as potential sources for novel antibiotic leads and presents the diazaquinomycins as potent and selective inhibitors of M. tuberculosis.
Potential Chemopreventive Activity of a New Macrolide Antibiotic from a Marine-Derived Micromonospora sp.
Skylar Carlson,Laura Marler,Sang Jip Nam,Bernard D. Santarsiero,John M. Pezzuto,Brian T. Murphy +5 more
TL;DR: A marine-derived actinomycete strain (CNJ-878) that exhibited activity with cultured Hepa 1c1c7 cells is identified, and a new macrolide, juvenimicin C, is reported, the first reported member of the macrolides class of antibiotics found to mediate these responses.
Phylum-Specific Regulation of Resistomycin Production in a Streptomyces sp. via Microbial Coculture
TL;DR: A lack of promiscuity of antibiotic biosynthetic pathway regulation is suggested and it is indicated that it is feasible to mine existing microbial strain libraries for antibiotics in a phylum-specific manner.
27