11 Papers
Siyu Ma is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Chemistry & Cancer research. The author has an hindex of 4, co-authored 6 publications.
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Papers
Smart biomimetic metal organic frameworks based on ROS-ferroptosis-glycolysis regulation for enhanced tumor chemo-immunotherapy
Jie Yang,Siyu Ma,Rui Xu,Yawen Wei,Jun Zhang,Tiantian Zuo,Zhihua Wang,Huizi Deng,Ning Yang,Qi Shen +9 more
TL;DR: In this paper, a cancer cell membrane coated metal organic framework (MOF) loading with glucose oxidase (GOx) and doxorubicin (DOX) was constructed (denoted as mFe(SS)/DG).
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Heparanase-driven sequential released nanoparticles for ferroptosis and tumor microenvironment modulations synergism in breast cancer therapy.
Jun Zhang,Jie Yang,Tiantian Zuo,Siyu Ma,Nadira Xokrat,Zongwei Hu,Zhihua Wang,Rui Xu,Yawen Wei,Qi Shen +9 more
TL;DR: NLC/H(D +-F + S) NPs was a novel dosage regimen for breast cancer therapy through intracellular and extracellular mechanisms, in which ferroptosis induced by ROS played an important role.
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Chemodynamic and Photothermal Combination Therapy Based on Dual-Modified Metal-Organic Framework for Inducing Tumor Ferroptosis/Pyroptosis.
TL;DR: Overall, MP@PI is a kind of promising cancer therapy strategy through CDT and PTT combination, inducing ferroptosis and pyroPTosis, and evokes the immune response in vivo and enhances the antitumor effects further.
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Ferroptosis/pyroptosis dual-inductive combinational anti-cancer therapy achieved by transferrin decorated nanoMOF
Rui Xu,Jie Yang,Yun Qian,Huizi Deng,Zhihua Wang,Siyu Ma,Yawen Wei,Ning Yang,Qi Shen +8 more
- 06 Apr 2021
TL;DR: In this paper, a dual-inductive nano-system to realize ferroptosis/pyro-ptosis mediated anti-cancer effects is presented, where the nanodrug (Tf-LipoMof@PL) is constructed with a piperlongumine loaded metal-organic framework (MOF) coated with transferrin decorated pH sensitive lipid layer.
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Reactive oxygen species / photothermal therapy dual-triggered biomimetic gold nanocages nanoplatform for combination cancer therapy via ferroptosis and tumor-associated macrophage repolarization mechanism.
TL;DR: In this paper, a cancer cell membrane-camouflaged gold nanocage loading doxorubicin (DOX) and l -buthionine sulfoximine (BSO) was constructed as an innovative nanoplatform to confer promising cancer combination therapy by evoking effective ferroptosis and immune responses.
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