Siwei Yan
Xiamen University
8 Papers
7 Citations
Siwei Yan is an academic researcher from Xiamen University. The author has contributed to research in topics: Celastrol & Chemistry. The author has an hindex of 3, co-authored 4 publications.
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Papers
SAR study of celastrol analogs targeting Nur77-mediated inflammatory pathway.
Ziwen Chen,Duo Zhang,Siwei Yan,Chaochao Hu,Zhenfei Huang,Zhuoer Li,Shuangzhou Peng,Xiaotong Li,Yi Zhu,Hongyu Yu,Baohuan Lian,Qi Kang,Mingyu Li,Zhiping Zeng,Xiao-kun Zhang,Ying Su,Ying Su +16 more
TL;DR: The design, synthesis, SAR study, biological evaluation and biological evaluation of a series of celastrol analogs found that compound 3a with a Kd of 0.87 μM was found to be less toxic than Celastrol and could be a hit molecule for further optimization.
35
AlCl3·6H2O-Catalyzed Friedel-Crafts Alkylation of Indoles by the para-Quinone Methide Moiety of Celastrol
Yi Zhu,Ziwen Chen,Zhenfei Huang,Siwei Yan,Zhuoer Li,Hu Zhou,Xiao-kun Zhang,Xiao-kun Zhang,Ying Su,Ying Su,Zhiping Zeng +10 more
TL;DR: A classical Friedel-Crafts alkylation of different indoles catalyzed by AlCl3·6H2O has been developed for a well-known important natural product, celastrol, resulting in a series of derivatives for further biological evaluation.
Investigation of Ce/BEA as a passive NO adsorber: 1. The occurrences of cerium and adsorption behavior
Min-Jun Yu,Yiying Ding,Xiaojie Yu,Siwei Yan,Meiqing Shen,Jianqiang Wang,Jun Wang,Gurong Shen +7 more
TL;DR: Ce/BEA was synthesized by ion exchange method to identify the active species in NOx adsorption, compared with aggregated Ce species in Ce/SiAlOx prepared by impregnation method as discussed by the authors .
2
Correlation of phase equilibria for gas hydrates in organic inhibitor aqueous solutions within wide concentration range
TL;DR: In this paper , the Chen-Guo model was used to calculate the phase equilibria of simple gas hydrates and a new aw correlation was proposed to realize the description of gas hyddrates in the organic inhibitor solutions.
1
Patent
Triterpenoid compounds, pharmaceutical compositions thereof, and their use for treating nuclear receptor subfamily 4 group member 1-mediated disease
Xiao-kun Zhang,Ying Su,Guobin Xie,Zhenfei Huang,Ziwen Chen,Zhuo Yuqi,Zhang Duo,Zhiping Zeng,Siwei Yan +8 more
- 18 Mar 2021
TL;DR: In this paper, triterpenoid compounds, for example, a compound of Formula (I), and pharmaceutical compositions thereof, are discussed, and methods of their use for treat.