Addiction is a compulsive brain disorder that cause the use of substance despite harmful sideeffects.The abuse of drugs and alcohol is the leading cause of preventable illnesses and premature death in our society. Many factors like genetic and environmental factors play a major role in addiction. Neuromodulation provides us with a unique opportunity to directly apply neuroscientific knowledge to the treatment of addiction. It will remain that the treatment is mainly for psychosocial and behavioral interventions.

/pdf/understanding-substance-abuse-and-addiction-12hh93h9ps.pdf

Understanding Substance Abuse and Addiction

There various methods adopted in synthetic organic chemistry including microwave assisted synthesis, sonochemistry and green chemistry Applications of all microwaves in the synthesis of chemical moieties which are biologically active have been discussed with a short briefing of advantages of these techniques over the conventional approaches

/pdf/a-review-on-recent-publications-using-microwaves-in-57szat1w5q.pdf

A Review on Recent Publications Using Microwaves in Synthesis of Biologically Active Molecules

Losing weight is a tougher thing than maintenance of a healthy weight as our daily routine is a eat and run including a massive portion sized culture. As we are tired of failing in weight loss make us to believe in dieting don’t work. Yes, we probably right as most of or diets don’t work but, it is not that the diet is wrong but it is the fact that all diets doesn’t work in the same manner on every one proving every individual responds to the diet of their suit. As there is no such one prescribed path to lose weight there are plenty of steps helpful in developing relationship with food which helps us to succeed in losing weight. This proves that healthing eating is one of the best tool to invade the weight loss.

/pdf/cutting-portions-without-feeling-hungry-3pviwu50mn.pdf

Cutting Portions without Feeling Hungry

Addiction is a disorder of the brain's reward system which arises through transcriptional and epigenetic mechanisms and arises over time from chronically high levels of coverage to an addictive stimulus (e.g., morphine, cocaine, sexual intercourse, gambling, etc.). Most drugs affect the brain's "reward circuit" by inundating it with the chemical messenger dopamine. This reward system controls the body's capability to feel pleasure and motivates a person to repeat behaviors needed to thrive, such as eating and spending time with loved ones. This overstimulation of the reward circuit causes the extremely pleasurable "high" that can lead people to take a drug again and again.

/pdf/addiction-current-updates-59eperk5c6.pdf

Addiction: Current Updates

/pdf/research-reviews-journal-of-nursing-health-sciences-2v5793dwyz.pdf

Research & Reviews: Journal of Nursing & Health Sciences

Impact of Early Behavioral Modification in Food Addiction is Effective Method of Treating Obesity

Background: Head and neck cancers account for about 30% of all cancers in India. Studies showed that there is an increased primary DNA damage even before the commencement of any modality of treatment in cancer patients which is further increased by the treatment. Chemo-radiation induced DNA damage is not repaired so effectively in patients with carcinoma which might pave way for secondary carcinoma.
Aims and Objectives: The aim of this study was to assess the degree of DNA damage by comet assay technique in patients with head and neck carcinoma receiving radiotherapy. The degree of DNA damage was compared according to the age, gender, and associated risk factors of the patients.
Materials and Methods: 35 patients with Stages II, III, and IVA, histopathologically confirmed Squamous cell carcinoma of head and neck with Karnofsky Performance Status >70 attending radiotherapy OPD for treatment were included in this study.1 ml of heparinized blood was collected from the study participants during various doses of radiation treatment. All the samples were processed immediately and analyzed for DNA damage by single cell gel electrophoresis assay - Comet assay technique.
Results: The comet length parameter, head diameter, and tail length were found to be increased when compared to baseline sample. The percentage of DNA in head parameter of post-RT sample was decreased when compared to baseline sample All these findings are indicative of DNA damage following radiotherapy.
Conclusion: Patients with locally advanced head and neck carcinoma following radiotherapy showed a sequential increase in the DNA damage. The co-existing risk factors and old age may increase the baseline DNA damage in the patients with head and neck cancers.

Sequential evaluation of DNA damage in patients with head and neck carcinoma receiving radiotherapy

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Impact of Early Behavioral Modification in Food Addiction is Effective Method of Treating Obesity

Sequential evaluation of DNA damage in patients with head and neck carcinoma receiving radiotherapy