Sisi Chen
Chongqing Medical University
8 Papers
Sisi Chen is an academic researcher from Chongqing Medical University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 4, co-authored 5 publications.
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Papers
High-mobility group box-1 protein from CC10+ club cells promotes type 2 response in the later stage of respiratory syncytial virus infection
Sisi Chen,Guangyuan Yu,Jun Xie,Wei Tang,Leiqiong Gao,Xiaoru Long,Luo Ren,Xiaohong Xie,Yu Deng,Zhou Fu,Enmei Liu +10 more
TL;DR: A link between viral infection and the asthma-like type 2 responses that are associated with long-term consequences is revealed and high-mobility group box-1 (HMGB1) protein promotes the type 2 response in the later stage of RSV infection.
24
HMGB1 mediates HAdV-7 infection-induced pulmonary inflammation in mice
TL;DR: HMGB1 promotes HAdV-7 replication and signals throughTLR-4, TLR-9, and RAGE receptors to activate NF-κB, stimulating the release of inflammatory mediators and contributing to adenoviral pathology.
22
CXCL12/CXCR4 Axis is Involved in the Recruitment of NK Cells by HMGB1 Contributing to Persistent Airway Inflammation and AHR During the Late Stage of RSV Infection
TL;DR: CXCL12/CXCR4 axis is involved in the recruitment of NK cells by HMGB1, contributing to persistent airway inflammation and AHR during the late stage of RSV infection.
6
A pilot study exploring the association of bronchial bacterial microbiota and recurrent wheezing in infants with atopy
Wei Tang,Lei Zhang,Tao Ai,Wanmin Xia,Cheng Xie,Yinghong Fan,Sisi Chen,Zijin Chen,Jiawei Yao,Yiping Peng +9 more
TL;DR: In this paper , the authors analyzed the bronchial bacterial microbiota of infants with recurrent wheezing and with or without atopic diseases using a systems biology approach, and found that atopic infants showed a significantly higher abundance in two phyla (Deinococcota and unidentified bacteria) and one genus (Haemophilus) and a significantly lower abundance in one phylum (Actinobacteria).