Sinan Wang
University of California, San Francisco
7 Papers
19 Citations
Sinan Wang is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Hyperpolarization (physics) & Prostate. The author has an hindex of 3, co-authored 7 publications.
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Papers
Late-stage deuteration of 13C-enriched substrates for T1 prolongation in hyperpolarized 13C MRI
Céline Taglang,David E. Korenchan,Cornelius von Morze,Justin Yu,Chloé Najac,Sinan Wang,Joseph E. Blecha,Sukumar Subramaniam,Robert Bok,Henry F. VanBrocklin,Daniel B. Vigneron,Sabrina M. Ronen,Renuka Sriram,John Kurhanewicz,David M. Wilson,Robert R. Flavell +15 more
TL;DR: A robust and selective late-stage deuteration methodology was applied to 13C-enriched amino and alpha hydroxy acids to increase spin-lattice relaxation constant T1 for hyperpolarized 13C magnetic resonance imaging, demonstrating a kinetic isotope effect.
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Synthesis of N-trifluoromethyl amides from carboxylic acids
Jianbo Liu,Jianbo Liu,Matthew F.L. Parker,Sinan Wang,Robert R. Flavell,F. Dean Toste,David M. Wilson +6 more
TL;DR: In this article, isothiocyanates are desulfurized with AgF, and then the formed derivative is acylated to afford N-trifluoromethyl amides.
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Synthesis and Preliminary Biological Assessment of Carborane-Loaded Theranostic Nanoparticles to Target Prostate-Specific Membrane Antigen.
Niranjan Meher,Kyounghee Seo,Sinan Wang,Anil Parsram Bidkar,Miko Fogarty,Suchi Dhrona,Xiao Huang,Ryan Tang,Charles Blaha,Michael J. Evans,David R. Raleigh,Young-wook Jun,Henry F. VanBrocklin,Tejal A. Desai,David M. Wilson,Tomoko Ozawa,Robert R. Flavell +16 more
TL;DR: Boron neutron capture therapy (BNCT) is an encouraging therapeutic modality for cancer treatment as mentioned in this paper, which is used for prostate specific membrane antigen (PSMA) is a cell membrane protein that is abundantly overexpress...
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Amino Acid-Derived Sensors for Specific Zn 2+ Detection Using Hyperpolarized 13 C Magnetic Resonance Spectroscopy
Sinan Wang,David E. Korenchan,Paola M. Perez,Céline Taglang,Thomas R. Hayes,Renuka Sriram,Robert Bok,Andrew S. Hong,Yunkou Wu,Henry Li,Zhen J. Wang,John Kurhanewicz,David M. Wilson,Robert R. Flavell +13 more
TL;DR: In this paper, enriched [1-13 C]cysteine and [1 -13 C2 ]iminodiacetic acid were developed as Zn2+ -specific imaging probes using hyperpolarized 13 C magnetic resonance spectroscopy.
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Tumor Microenvironment Biosensors for Hyperpolarized Carbon-13 Magnetic Resonance Spectroscopy.
TL;DR: In this paper, a review highlights the potential use of MRS to study features of the TME-elevated export of lactate, reduced interstitial pH, imbalanced redox equilibrium, and altered metal homeostasis.
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