PROBLEM TO BE SOLVED: To provide a bicyclic heterocycle derivative for treating or preventing obesity, diabetes, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of GPR119 in a patient.SOLUTION: There are provided bicyclic heterocycle derivatives, compositions comprising the bicyclic heterocycle derivative, and methods of using the bicyclic heterocycle derivatives for treating or preventing obesity, diabetes, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of GPR119 in a patient. Compounds of formulas (I), (II), (III) and (IV) and pharmaceutically acceptable salts, solvates, esters or prodrugs thereof (referred to collectively herein as the "bicyclic heterocycle derivatives") can be useful for treating or preventing the obesity, the diabetes, a diabetic complication, metabolic syndrome, the cardiovascular disease or the disorder related to the activity of GPR119 (each being a "condition") in a patient.

Bicyclic heterocycle derivative and use thereof as modulator of activity of gpr119

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