Simone Schmidt
Leibniz University of Hanover
6 Papers
45 Citations
Simone Schmidt is an academic researcher from Leibniz University of Hanover. The author has contributed to research in topics: Eicosapentaenoic acid & Docosahexaenoic acid. The author has an hindex of 6, co-authored 6 publications.
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Papers
Comparison of free serum oxylipin concentrations in hyper- vs. normolipidemic men
Jan Philipp Schuchardt,Simone Schmidt,Gaby Kressel,Hua Dong,Ina Willenberg,Bruce D. Hammock,Andreas Hahn,Nils Helge Schebb +7 more
TL;DR: Overall the hydroxy-, epoxy- and dihydroxy-FA levels were not changed suggesting that mild combined hyperlipidemia has no apparent effect on the concentration of circulating oxylipins, and a strong correlation between the EPA content in the erythrocyte membrane and the serum concentration of EPA derived oxylips was observed.
Modulation of blood oxylipin levels by long-chain omega-3 fatty acid supplementation in hyper- and normolipidemic men.
Jan Philipp Schuchardt,Simone Schmidt,Gaby Kressel,Ina Willenberg,Bruce D. Hammock,Andreas Hahn,Nils Helge Schebb +6 more
TL;DR: The dietary LC PUFA composition has a direct influence on the endogenous oxylipin profile, including several highly biological active EPA- and DHA-derived lipid mediators.
Transcriptome-based identification of antioxidative gene expression after fish oil supplementation in normo- and dyslipidemic men
Simone Schmidt,Frank Stahl,Kai Oliver Mutz,Thomas Scheper,Andreas Hahn,Jan Philipp Schuchardt +5 more
TL;DR: Investigation of the effects of n-3 PUFA supplementation on expression changes of genes involved in oxidative processes found an increased expression of antioxidative enzymes and a decreased expression of pro-oxidative and tissue enzymes, in both normo- and dyslipidemic men.
Regulation of lipid metabolism-related gene expression in whole blood cells of normo- and dyslipidemic men after fish oil supplementation
Simone Schmidt,Janina Willers,Frank Stahl,Kai-Oliver Mutz,Thomas Scheper,Andreas Hahn,Jan Philipp Schuchardt +6 more
TL;DR: Gene expression analyses revealed several possible molecular pathways by which n-3 PUFAs lower the TG level and increase the HDL-C and low-density lipoprotein level, whereupon the regulation of PPARα appear to play a central role.
Different gene expression profiles in normo- and dyslipidemic men after fish oil supplementation: results from a randomized controlled trial.
Simone Schmidt,Frank Stahl,Kai-Oliver Mutz,Thomas Scheper,Andreas Hahn,Jan Philipp Schuchardt +5 more
TL;DR: This is the first study showing significant differences in gene expression profiles between normo- and dyslipidemic men after FO supplementation, indicating the immune-modulatory and anti-inflammatory capability of FO and its bioactive FAs, eicosapentaenoic acids and docosahexaenoic acid.