Simona Zingaro
5 Papers
Simona Zingaro is an academic researcher. The author has contributed to research in topics: Biology & Haematopoiesis. The author has an hindex of 1, co-authored 3 publications.
Chat about Author
Papers
Pressure and stiffness sensing together regulate vascular smooth muscle cell phenotype switching
Pamela Swiatlowska,Brian Sit,Zheng Feng,Emilie Marhuenda,Ioannis Xanthis,Simona Zingaro,Matthew Ward,Xinmiao Zhou,Qingzhong Xiao,Catherine M. Shanahan,Gareth E. Jones,Cheng-han Yu,Thomas Iskratsch +12 more
TL;DR: It is found that pressure and stiffness individually affect the VSMC phenotype, but only the combination of hypertensive pressure and matrix compliance, and as such mechanical stimuli that are prevalent during atherosclerosis, leads to a full phenotypic switch including the formation of matrix-degrading podosomes.
33
Hematopoietic Stem/Progenitor Cells and Engineering: INVESTIGATING THE EXTRACELLULAR MICROENVIRONMENT AS A POTENTIAL TARGET TO MONITOR AND CONTROL LARGE-SCALE HAEMOPOIETIC DIFFERENTIATION
Margit Henry,Claire O'Grady,Simona Zingaro,Charlotte Lee-Reeves,Limor Zwi-Dantsis,Christopher Dubois,Mahen Jayawardena,Abhilash S. Nair,Sunitha Menon,Miranda Smart,Jahid Hasan +10 more
Extracellular vesicles stimulate smooth muscle cell migration by presenting collagen VI
A. Kapustin,S. S. Tsakali,Meredith Whitehead,George Chennell,Meng-Ying Wu,C. Molenaar,Anton G. Kutikhin,L. A. Bogdanov,Maxim Yu. Sinitsky,Kseniya A. Rubina,Aled Clayton,Frederik J. Verweij,D. Michiel Pegtel,Simona Zingaro,Arseniy A. Lobov,B. Zainullina,Dylan Owen,Maddy Parsons,Richard E. Cheney,Derek T. Warren,Martin J. Humphries,Thomas Iskratsch,Mark R. Holt,Catherine M. Shanahan +23 more
TL;DR: Data suggests that the accumulation of FN is a key early event in vessel repair acting to promote secretion of collage VI enriched sEVs by VSMCs, which stimulate migration and invasion in blood vessel repair.
Simplifying ipsc to nk manufacturing using automated bioprocessing and deeper process and product characterisation.
M.F. Mata,J. Guenat,M. Henry,V.D. Fernandez,M. Tregidgo,M. Jayawardena,P. Statham,Charlotte Lee-Reeves,A. Karachaliou,Simona Zingaro,A. Nair,A. Podovei,C. O'Grady,D. Marginean,M. Tarunina,T. Ponomaryov,J. Hasan +16 more