Simon Minovitsky
Lawrence Berkeley National Laboratory
14 Papers
790 Citations
Simon Minovitsky is an academic researcher from Lawrence Berkeley National Laboratory. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 10, co-authored 14 publications.
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Papers
In vivo enhancer analysis of human conserved non-coding sequences
Len A. Pennacchio,Len A. Pennacchio,Nadav Ahituv,Alan M. Moses,Shyam Prabhakar,Marcelo A. Nobrega,Marcelo A. Nobrega,Malak Shoukry,Simon Minovitsky,Inna Dubchak,Inna Dubchak,Amy Holt,Keith D. Lewis,Ingrid Plajzer-Frick,Jennifer A. Akiyama,Sarah De Val,Veena Afzal,Brian L. Black,Olivier Couronne,Olivier Couronne,Michael B. Eisen,Michael B. Eisen,Axel Visel,Edward M. Rubin,Edward M. Rubin +24 more
TL;DR: This study characterized the in vivo enhancer activity of a large group of non-coding elements in the human genome that are conserved in human–pufferfish, Takifugu (Fugu) rubripes, or ultraconserved in human-mouse–rat.
VISTA Enhancer Browser—a database of tissue-specific human enhancers
TL;DR: The VISTA Enhancer Browser as discussed by the authors is a collection of more than 250 experimentally tested DNA fragments, of which more than 100 have been validated as tissue-specific enhancers, and provides digital images of whole-mount embryo staining at embryonic day 11.5 and anatomical description of the reporter gene expression pattern.
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VISTA Enhancer Browser--A Database of Tissue-Specific Human Enhancers - eScholarship
Axel Visel,Simon Minovitsky,Inna Dubchak,Len A. Pennacchio +3 more
- 01 Aug 2006
TL;DR: Comparison genome analysis is utilized to identify candidate enhancer elements in the human genome coupled with the experimental determination of their in vivo enhancer activity in transgenic mice, and experimentally validated training sets are expected to provide a basis for a wide range of downstream computational and functional studies of enhancer function.
The Genome Portal of the Department of Energy Joint Genome Institute
Igor V. Grigoriev,Henrik P. Nordberg,Igor Shabalov,Andrea Aerts,Michael N. Cantor,David Goodstein,Alan Kuo,Simon Minovitsky,Roman Nikitin,Robin A. Ohm,Robert Otillar,Alexander Poliakov,Igor Ratnere,Robert Riley,Tatyana Smirnova,Daniel S. Rokhsar,Inna Dubchak +16 more
TL;DR: The general organization of the JGI Genome Portal is described and the most recent addition, MycoCosm, a new integrated fungal genomics resource is described.
Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors
Sarah De Val,Neil C. Chi,Stryder M. Meadows,Simon Minovitsky,Joshua P. Anderson,Ian S. Harris,Melissa L. Ehlers,Pooja Agarwal,Axel Visel,Shan Mei Xu,Len A. Pennacchio,Inna Dubchak,Paul A. Krieg,Didier Y.R. Stainier,Brian L. Black +14 more
TL;DR: It is demonstrated that coexpression of the Forkhead protein FoxC2 and the Ets protein Etv2 induces ectopic expression of vascular genes in Xenopus embryos, and that combinatorial knockdown of the orthologous genes in zebrafish embryos disrupts vascular development.
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