Simon Crawford
Monash University
4 Papers
9 Citations
Simon Crawford is an academic researcher from Monash University. The author has contributed to research in topics: Mitochondrion & Messenger RNA. The author has an hindex of 2, co-authored 4 publications.
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Papers
Disruption of mitochondrial dynamics affects behaviour and lifespan in Caenorhabditis elegans.
Joseph J. Byrne,Ming S. Soh,Gursimran Chandhok,Tarika Vijayaraghavan,Jean-Sébastien Teoh,Simon Crawford,Ansa Emmanuel Cobham,Nethmi M. B. Yapa,Christen K. Mirth,Brent Neumann +9 more
TL;DR: The results reveal that disruption of fusion induces more profound defects than lack of fission on animal behaviour and tissue function, and imply that while fusion is required throughout life, fission is more important later in life likely to combat ageing-associated stressors.
Tandem RNA binding sites induce self-association of the stress granule marker protein TIA-1.
Fionna E. Loughlin,Danella L West,Menachem J. Gunzburg,Saboora Waris,Simon Crawford,Matthew C.J. Wilce,Jacqueline A. Wilce +6 more
TL;DR: In this paper, the authors investigated the self-associating properties of full-length TIA-1 in the presence of designed and native TIA1 nucleic acid binding sites in vitro, monitoring phase separation, fibril formation and shape.
Chromosome Segregation and Peptidoglycan Remodeling Are Coordinated at a Highly Stabilized Septal Pore to Maintain Bacterial Spore Development
Ahmed M.T. Mohamed,Helena Chan,Johana Luhur,Elda Bauda,Benoit Gallet,Cécile Morlot,Louise Cole,Milena M. Awad,Simon Crawford,Dena Lyras,David Z. Rudner,Christopher D. A. Rodrigues +11 more
TL;DR: In this paper, the authors used Bacillus subtilis to identify factors that revealed the link between chromosome translocation and peptidoglycan remodeling, and showed that these factors ensure coordination between the two processes.
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Characterisation of the Myocardial Mitochondria Structural and Functional Phenotype in a Murine Model of Diabetic Cardiomyopathy.
Alex M. Parker,Alex M. Parker,Alex M. Parker,Mitchel Tate,Mitchel Tate,Darnel Prakoso,Darnel Prakoso,M. Deo,Andrew M. Willis,David M. Nash,D. Donner,D. Donner,Simon Crawford,Helen Kiriazis,Helen Kiriazis,Cesare Granata,Cesare Granata,Melinda T. Coughlan,Miles J. De Blasio,Miles J. De Blasio,Rebecca H. Ritchie +20 more
TL;DR: In this paper, a mouse model of diabetic cardiomyopathy was used to characterise impairments in mitochondria structure and function in a 6-week-old male FVB/N mice by the combination of three consecutive-daily injections of low-dose streptozotocin (STZ, each 55 mg/kg i.p.) and high-fat diet (42% fat from lipids).