Silvia Speca
university of lille
40 Papers
131 Citations
Silvia Speca is an academic researcher from university of lille. The author has contributed to research in topics: Fibrosis & Medicine. The author has an hindex of 17, co-authored 35 publications. Previous affiliations of Silvia Speca include University of L'Aquila & French Institute of Health and Medical Research.
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Papers
Cellular and molecular mechanisms of intestinal fibrosis
TL;DR: Def definition of the cellular and molecular mechanisms involved in intestinal fibrosis may provide the key to developing new therapeutic approaches.
264
Cellular and Molecular Mediators of Intestinal Fibrosis.
Ian C. Lawrance,Ian C. Lawrance,Gerhard Rogler,Giorgos Bamias,Christine Breynaert,Jon Florholmen,Gianluca Pellino,Shimon Reif,Silvia Speca,Giovanni Latella +9 more
TL;DR: The aim is to heighten the understanding of the factors involved in intestinal fibrogenesis so that detailed research can be encouraged in order to advance the processes that could lead to effective treatments.
162
Luteolin prevents irinotecan-induced intestinal mucositis in mice through antioxidant and anti-inflammatory properties
Thaise Boeing,Priscila de Souza,Silvia Speca,Lincon Bordignon Somensi,Luísa Nathália Bolda Mariano,Benhur Judah Cury,Mariana Ferreira dos Anjos,Nara Lins Meira Quintão,Laurent Dubuqoy,Pierre Desreumax,Luisa Mota da Silva,Sérgio Faloni de Andrade +11 more
TL;DR: The activity of the flavonoid luteolin is evaluated for mucosal damage caused by cancer treatment, which has never been tested for this purpose despite its biological potential.
113
•Journal Article
Can we prevent, reduce or reverse intestinal fibrosis in IBD?
TL;DR: There are important clinical issues that need further investigations, in particular the identification of factors relevant for the development of the intestinal fibrosis in IBD and the need of accurate and effective monitoring of the fibrotic progression and of effectiveness of the new proposed treatments.