Silvia Polidoro
Imperial College London
11 Papers
6 Citations
Silvia Polidoro is an academic researcher from Imperial College London. The author has contributed to research in topics: DNA methylation & Epigenetics. The author has an hindex of 5, co-authored 11 publications.
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Papers
Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging.
Daniel L. McCartney,Josine L. Min,Rebecca C Richmond,Ake T. Lu,Maria K. Sobczyk,Gail Davies,Linda Broer,Xiuqing Guo,Ayoung Jeong,Ayoung Jeong,Jeesun Jung,Silva Kasela,Seyma Katrinli,Pei-Lun Kuo,Pamela R. Matias-Garcia,Pashupati P. Mishra,Marianne Nygaard,Marianne Nygaard,Teemu Palviainen,Amit Patki,Laura M. Raffield,Scott M. Ratliff,Tom G. Richardson,Oliver Robinson,Mette Soerensen,Mette Soerensen,Dianjianyi Sun,Pei-Chien Tsai,Pei-Chien Tsai,Pei-Chien Tsai,Matthijs D. van der Zee,Matthijs D. van der Zee,Rosie M. Walker,Xiaochuan Wang,Yunzhang Wang,Rui Xia,Zongli Xu,Jie Yao,Wei Zhao,Adolfo Correa,Eric Boerwinkle,Pierre Antoine Dugué,Pierre Antoine Dugué,Pierre Antoine Dugué,Peter Durda,Hannah R Elliott,Christian Gieger,Eco J. C. de Geus,Eco J. C. de Geus,Sarah E. Harris,Gibran Hemani,Medea Imboden,Medea Imboden,Mika Kähönen,Sharon L.R. Kardia,Jacob K. Kresovich,Shengxu Li,Kathryn L. Lunetta,Massimo Mangino,Massimo Mangino,Dan Mason,Andrew M. McIntosh,Jonas Mengel-From,Jonas Mengel-From,Ann Zenobia Moore,Joanne M. Murabito,Miina Ollikainen,James S. Pankow,Nancy L. Pedersen,Annette Peters,Silvia Polidoro,David J. Porteous,Olli T. Raitakari,Olli T. Raitakari,Stephen S. Rich,Dale P. Sandler,Elina Sillanpää,Elina Sillanpää,Alicia K. Smith,Melissa C. Southey,Melissa C. Southey,Melissa C. Southey,Konstantin Strauch,Konstantin Strauch,Hemant K. Tiwari,Toshiko Tanaka,Therese Tillin,André G. Uitterlinden,David Van Den Berg,Jenny van Dongen,Jenny van Dongen,James G. Wilson,James G. Wilson,John Wright,Idil Yet,Idil Yet,Donna K. Arnett,Stefania Bandinelli,Jordana T. Bell,Alexandra M. Binder,Dorret I. Boomsma,Dorret I. Boomsma,Wei Chen,Kaare Christensen,Kaare Christensen,Karen N. Conneely,Paul Elliott,Luigi Ferrucci,Myriam Fornage,Sara Hägg,Caroline Hayward,Marguerite R. Irvin,Jaakko Kaprio,Debbie A Lawlor,Terho Lehtimäki,Falk W. Lohoff,Lili Milani,Roger L. Milne,Roger L. Milne,Roger L. Milne,Nicole Probst-Hensch,Nicole Probst-Hensch,Alexander P. Reiner,Beate Ritz,Jerome I. Rotter,Jennifer A. Smith,Jack A. Taylor,Joyce B. J. van Meurs,Paolo Vineis,Melanie Waldenberger,Ian J. Deary,Caroline L Relton,Steve Horvath,Riccardo E. Marioni +133 more
TL;DR: In this article, the authors identify 137 genome-wide significant loci, of which 113 are novel, from genomewide association study (GWAS) meta-analyses of four epigenetic clocks and epigenetic surrogate markers for granulocyte proportions and plasminogen activator inhibitor 1 levels.
Determinants of accelerated metabolomic and epigenetic aging in a UK cohort
Oliver Robinson,Marc Chadeau Hyam,Ibrahim Karaman,Rui Pinto,Mika Ala-Korpela,Mika Ala-Korpela,Evangelos Handakas,Giovanni Fiorito,Giovanni Fiorito,He Gao,Andy Heard,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Matthew M. Lewis,Raha Pazoki,Raha Pazoki,Silvia Polidoro,Ioanna Tzoulaki,Matthias Wielscher,Paul Elliott,Paolo Vineis +21 more
TL;DR: In conclusion, metabolomics is a promising approach for the assessment of biological age and appears complementary to established epigenetic clocks.
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Age-related DNA methylation changes are sex-specific: a comprehensive assessment.
I. I. Yusipov,Maria Giulia Bacalini,Alena I. Kalyakulina,Mikhail Krivonosov,Chiara Pirazzini,Noémie Gensous,Francesco Ravaioli,Maddalena Milazzo,Cristina Giuliani,Cristina Giuliani,Maria Vedunova,Giovanni Fiorito,Giovanni Fiorito,Amedeo Gagliardi,Silvia Polidoro,Paolo Garagnani,Mikhail Ivanchenko,Claudio Franceschi +17 more
- 03 Dec 2020
TL;DR: A meta-analysis of 4 large whole blood datasets comparing 4 aspects of epigenetic age-dependent remodeling between the two sexes found that a large fraction (43%) of sex-associated probes undergoes age-associated DNA methylation changes, and that a limited number of probes show age-by-sex interaction.
Age-related DNA methylation changes are sex-specific: a comprehensive assessment
I. I. Yusipov,Maria Giulia Bacalini,Alena I. Kalyakulina,Mikhail Krivonosov,Chiara Pirazzini,Noémie Gensous,Francesco Ravaioli,Maddalena Milazzo,Cristina Giuliani,Cristina Giuliani,Maria Vedunova,Giovanni Fiorito,Giovanni Fiorito,Amedeo Gagliardi,Silvia Polidoro,Paolo Garagnani,Mikhail Ivanchenko,Claudio Franceschi +17 more
TL;DR: A meta-analysis of 4 large whole blood datasets comparing 4 aspects of epigenetic age-dependent remodeling between the two sexes found that a large fraction (43%) of sex-associated probes undergoes age-associated DNA methylation changes, and that a limited number of probes shows age-by-sex interaction.
Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption.
Irma Karabegović,Eliana Portilla-Fernandez,Yang Li,Jiantao Ma,Jiantao Ma,Silvana C.E. Maas,Daokun Sun,Emily A Hu,Brigitte Kühnel,Yan Zhang,Srikant Ambatipudi,Srikant Ambatipudi,Srikant Ambatipudi,Giovanni Fiorito,Giovanni Fiorito,Jian Huang,Juan E. Castillo-Fernandez,Juan E. Castillo-Fernandez,Kerri L. Wiggins,Niek de Klein,Sara Grioni,Brenton R. Swenson,Silvia Polidoro,Jorien L. Treur,Cyrille Cuenin,Pei-Chien Tsai,Pei-Chien Tsai,Pei-Chien Tsai,Ricardo Costeira,Veronique Chajes,Kim V.E. Braun,Niek Verweij,Anja Kretschmer,Lude Franke,Joyce B. J. van Meurs,André G. Uitterlinden,Robert J. de Knegt,M. Arfan Ikram,Abbas Dehghan,Annette Peters,Ben Schöttker,Sina A. Gharib,Nona Sotoodehnia,Jordana T. Bell,Paul R. Elliott,Paolo Vineis,Caroline L Relton,Zdenko Herceg,Hermann Brenner,Melanie Waldenberger,Casey M. Rebholz,Trudy Voortman,Qiuwei Pan,Myriam Fornage,Dan D. Levy,Manfred Kayser,Mohsen Ghanbari,Mohsen Ghanbari +57 more
TL;DR: In this article, the results from epigenome-wide association studies (EWAS) on coffee and tea consumption in 15,789 participants of European and African-American ancestries from 15 cohorts were reported.