Sian Chen
Wenzhou Medical College
5 Papers
16 Citations
Sian Chen is an academic researcher from Wenzhou Medical College. The author has contributed to research in topics: Downregulation and upregulation & Wnt signaling pathway. The author has an hindex of 1, co-authored 5 publications.
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Papers
NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation.
Yuanbo Hu,Chenbin Chen,Xinya Tong,Sian Chen,Xianjing Hu,Bujian Pan,Xiangwei Sun,Zhiyuan Chen,Xinyu Shi,Yingying Hu,Xian Shen,Xiangyang Xue,Mingdong Lu +12 more
TL;DR: The 5-methylcytosine (m5C) RNA methyltransferase NSUN2 is involved in the regulation of cell proliferation and metastasis formation and is upregulated in multiple cancers as mentioned in this paper.
Commensal flora triggered target anti-inflammation of alginate-curcumin micelle for ulcerative colitis treatment
Wang Yanan,Li Yanan,Lingyun He,Baiping Mao,Sian Chen,Vanessa Martinez,Xiaoling Guo,Xian Shen,Baohua Liu,Chao Li +9 more
TL;DR: In this paper, a stable Alginate-Curcumin conjugate (Alg-Cur) micelle was constructed in physiological solutions and compared with crystalline Cur, the target anti-inflammatory activities of AlgCur were systematically investigated.
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Three-Dimensional Ex Vivo Culture for Drug Responses of Patient-Derived Gastric Cancer Tissue.
Sian Chen,Chenbin Chen,Yuanbo Hu,Ce Zhu,Xiaozhi Luo,Lizhu Wang,Xiang Wang,Xiangwei Sun,Xiaodong Chen,Wangkai Xie,Han Lou,Xielin Huang,Chao Li,Jun Xu,Xiangyang Xue,Xian Shen +15 more
TL;DR: In this paper, a 3D culturing platform was proposed to accurately predict drug responses in a time and cost-effective manner for gastric cancer (GC) in a clinical setting.
A facile assay for rapid detection of COVID-19 antibodies
Caixia Liu,Baiping Mao,Vanessa Martinez,Xiaojian Chen,Li Yanan,Lingyun He,Sian Chen,Xiaoling Guo,Xian Shen,Xiandan Bao,Haifa Shen,Stefania Lenna,Pinyi Qian,Lingzhi Wu,Chao Li +14 more
TL;DR: The principle and procedure of developing a colloidal gold immunochromatographic assay (GICA) for rapid detection of COVID-19-specific antibodies is presented and it is calculated that overall sensitivity and specificity of the assay were 95.85% and 97.47%, respectively.
The diverse roles of circular RNAs in pancreatic cancer.
TL;DR: In this article, the association between circRNAs and pancreatic cancer prognosis was discussed, and several compounds could regulate the expression of the non-coding RNAs, indicating that targeting circRNA by compounds might be helpful for treating pancreatic Cancer patients.