Si Jiang
Guangzhou Medical University
7 Papers
54 Citations
Si Jiang is an academic researcher from Guangzhou Medical University. The author has contributed to research in topics: Yellow fluorescent protein & Nuclear transport. The author has an hindex of 6, co-authored 7 publications.
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Papers
Probing the nuclear import signal and nuclear transport molecular determinants of PRV ICP22
Mingsheng Cai,Si Jiang,Zhancheng Zeng,Xiaowei Li,Chuncong Mo,Yanjia Yang,Chunke Chen,Peiping Xie,Yun Bian,Jinlin Wang,Jinlu Huang,Daixiong Chen,Tao Peng,Meili Li +13 more
TL;DR: The findings reported herein disclose the NLS and molecular mechanism for nuclear transport of P-ICP22, these results will uncover new avenues for depicting the biological roles of the P- ICP22 during PRV infection.
Characterization of the nuclear import and export signals of pseudorabies virus UL31.
Meili Li,Si Jiang,Jinlin Wang,Chuncong Mo,Zhancheng Zeng,Yanjia Yang,Chunke Chen,Xiaowei Li,Wei Cui,Jinlu Huang,Tao Peng,Mingsheng Cai +11 more
TL;DR: By transfection with a series of PRV UL31 deletion mutants fused to an enhanced yellow fluorescent protein (EYFP) gene, a bipartite nuclear localization signal (NLS) and a PY motif NLS of UL31 were identified and mapped to amino acids and the predicted nuclear export signal was shown to be nonfunctional.
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Identification of molecular determinants for the nuclear import of pseudorabies virus UL31.
Meili Li,Si Jiang,Chuncong Mo,Zhancheng Zeng,Xiaowei Li,Chunke Chen,Yanjia Yang,Jinlin Wang,Jinlu Huang,Daixiong Chen,Tao Peng,Mingsheng Cai +11 more
TL;DR: By utilizing live cells fluorescent microscopy, UL31 fused with enhanced yellow fluorescent protein was transiently expressed in live cells and confirmed to exclusively target to the nucleus in the absence of other viral proteins.
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Characterization of the subcellular localization and nuclear import molecular mechanisms of herpes simplex virus 1 UL2.
Mingsheng Cai,Zebin Huang,Zongmin Liao,Tao Chen,Ping Wang,Si Jiang,Daixiong Chen,Tao Peng,Yun Bian,Gengde Hong,Hang Yang,Zhancheng Zeng,Xiaowei Li,Meili Li +13 more
TL;DR: By using live cells fluorescent microscopy assay, UL2 tagged with enhanced yellow fluorescent protein was transiently expressed in live cells and showed a completely nuclear accumulation without the presence of other HSV-1 proteins, which will improve understanding of UL2-mediated biological functions in HSv-1 infection cycles.
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Characterization of the nuclear import signal of herpes simplex virus 1 UL31.
Mingsheng Cai,Daixiong Chen,Zhancheng Zeng,Hang Yang,Si Jiang,Xiaowei Li,Jingying Mai,Tao Peng,Meili Li +8 more
TL;DR: By transfection with a series of HSV-1 UL31 deletion mutants fused to enhanced yellow fluorescent protein, a bipartite nuclear localization signal (NLS) was identified and mapped to amino acids 1 to 27 and fluorescence results showed that the predicted nuclear export signal (NES) might be nonfunctional, and the functional NES of UL31 might require a specific conformation.
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