Shuxin Liang
Northwest A&F University
17 Papers
Shuxin Liang is an academic researcher from Northwest A&F University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 3, co-authored 4 publications.
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Papers
MicroRNA-27b Modulates Inflammatory Response and Apoptosis during Mycobacterium tuberculosis Infection.
Shuxin Liang,Zhigang Song,Yongyan Wu,Yuanpeng Gao,Mingqing Gao,Fayang Liu,Fengyu Wang,Yong Zhang +7 more
TL;DR: A novel role of the miR-27b/Bag2 axis is revealed in the regulation of inflammatory response and apoptosis and provide a potential molecular host defense mechanism against mycobacteria.
BAG2 ameliorates endoplasmic reticulum stress-induced cell apoptosis in Mycobacterium tuberculosis-infected macrophages through selective autophagy
TL;DR: It is indicated that BAG2 has anti-apoptotic effects on M. tuberculosis-induced ER stress, which is dependent on the promotion of autophagic flux and the induction of selective autophagy.
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SARS-CoV-2 spike protein induces IL-18-mediated cardiopulmonary inflammation via reduced mitophagy
Shuxin Liang,Changlei Bao,Zichao Yang,Shiyun Liu,Yanan Sun,Weitao Cao,Ting Wang,Tae-Hwi Schwantes-An,John S. Choy,Samisubbu R. Naidu,Ang Luo,Wen-Jin Yin,Stephen M. Black,Jian Wang,Pixin Ran,Ankit A. Desai,Haiyang Tang +16 more
TL;DR: In this paper , the authors identified IL-18 among 19 cytokines to stratify mortality and hospitalization burden in patients hospitalized with COVID-19 in patients with SARS-CoV-2 virus.
Mitochondrial Metabolism, Redox, and Calcium Homeostasis in Pulmonary Arterial Hypertension
TL;DR: This review focuses on mitochondrial metabolism alterations that occur in deranged pulmonary vessels and the right ventricle, including abnormalities in glycolysis and glucose oxidation, fatty acid oxidation, glutaminolysis, redox homeostasis, as well as iron and calcium metabolism.
SARS-CoV-2 spike protein receptor-binding domain perturbates intracellular calcium homeostasis and impairs pulmonary vascular endothelial cells
Kai-Chien Yang,Shiyun Liu,Han Yan,Wenju Lu,Haixia Chen,Changlei Bao,Huazhuo Feng,Jing Liao,Shuxin Liang,Li Xu,Haiyang Tang,Jason X.-J. Yuan,Nanshan Zhong,Jian Wang +13 more
TL;DR: Findings provide compelling evidence that S-RBD could induce persistent pulmonary vascular endothelial damage by binding to ACE2 and triggering [Ca^2+]_i through upregulation of Piezo1 and Orai1 and Targeted inhibition of ACE2-Piezo1/SOCC-[Ca^1+]-i axis proves a powerful strategy to treat S- RBD-induced pulmonary vascular diseases.
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