8 Papers
7 Citations
Shuo Yang is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Medicine & Visual field. The author has an hindex of 5, co-authored 7 publications.
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Papers
Long-term outcomes of gene therapy for the treatment of Leber's hereditary optic neuropathy.
Shuo Yang,Si-qi Ma,Xing Wan,Heng He,Han Pei,Min-jian Zhao,Chen Chen,Dao Wen Wang,Xiao-yan Dong,Jiajia Yuan,Bin Li +10 more
TL;DR: The results support the use of intravitreal rAAV2-ND4 as an aggressive maneuver in the clinical trial and further study in additional patients and in these 9 subjects is needed to better understand the effects of rAAv2- ND4 gene therapy on LHON and to increase the applications of this technique.
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Insulin Promotes Corneal Nerve Repair and Wound Healing in Type 1 Diabetic Mice by Enhancing Wnt/β-Catenin Signaling.
Shuo Yang,Yangyang Zhang,Zhaohua Zhang,Jing Dan,Qingjun Zhou,Xiaochuan Wang,Weina Li,Li Zhou,Lingling Yang,Lixin Xie +9 more
TL;DR: Investigation of the role of insulin in the diabetic cornea shows that insulin, via Wnt signaling, contributes to diabetic corneal epithelial wound healing and nerve injury recovery and is therefore, a potential protective factor for diabetic corney epithelial wounds and nerve injuries.
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The Landscape and Implications of Chimeric RNAs in Cervical Cancer.
TL;DR: It is believed that chimeric fusion RNAs generated by intergenic splicing represent a new repertoire of biomarkers and/or therapeutic targets for cancer, however, they would be missed when only genome sequences and fusions at DNA level are considered.
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Evaluation of Leber's hereditary optic neuropathy patients prior to a gene therapy clinical trial.
TL;DR: The effects of Leber hereditary optical neuropathy (LHON) gene therapy should be evaluated primarily based on visual acuity, and visual field, neural fiber thickness, and electrophysiology should be considered in the evaluation.
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Screening of Cervical Cancer with Self-Collected Cervical Samples and Next-Generation Sequencing
TL;DR: Current HPV testing methods with self-collected cervical samples are presented, focusing on recent advances in next-generation sequencing (NGS) technologies as a promising screening technology for cervical cancer precursors.
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