Shuo Chen
Harbin Medical University
4 Papers
Shuo Chen is an academic researcher from Harbin Medical University. The author has contributed to research in topics: Hypoxia (medical) & Medicine. The author has an hindex of 3, co-authored 4 publications.
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Papers
Reverse the down regulation of miR-92b-3p by hypoxia can suppress the proliferation of pulmonary artery smooth muscle cells by targeting USP28.
TL;DR: It is found that there was a significant negative relation between the level of miR-92b-3p and USP28 at protein level and reversed the down regulation of miP28 by hypoxia can suppress the proliferation of pulmonary artery smooth muscle cells by targetingUSP28.
22
Gastrodin causes vasodilation by activating KATP channels in vascular smooth muscles via PKA-dependent signaling pathway.
TL;DR: It is found that gastrodin is a activator of KATP in rat mesenteric artery smooth muscle cells, and this effect was eliminate by pre-treating with H89or PKI, PKA inhibitor and whole-cell patch-clamp recording techniques.
20
Allicin relaxes isolated mesenteric arteries through activation of PKA-KATP channel in rat.
TL;DR: Observations suggest that allicin exerts vasorelaxation effect through activation of PKA-KATP-signaling pathway throughactivation of KATP channels in rat MASMCs.
12
Down-regulation of lncRNA Gas5 promotes hypoxia-induced pulmonary arterial smooth muscle cell proliferation by regulating KCNK3 expression.
TL;DR: It is identified that Gas5/miR-23b-3p/KCNK3 axis may be a mechanism that hypoxia-induced PASMC proliferation and migration, providing a strategy for clinical treatment of HPH in the future.