Shuichi Takayama
Georgia Institute of Technology
394 Papers
4.1K Citations
Shuichi Takayama is an academic researcher from Georgia Institute of Technology. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 77, co-authored 361 publications. Previous affiliations of Shuichi Takayama include Parker H. Petit Institute for Bioengineering & Bioscience & Ulsan National Institute of Science and Technology.
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Papers
Phase-locked signals elucidate circuit architecture of an oscillatory pathway
Andreja Jovic,Bryan Howell,Michelle Cote,Susan M. Wade,Khamir Mehta,Atsushi Miyawaki,Richard R. Neubig,Jennifer J. Linderman,Shuichi Takayama +8 more
TL;DR: In this article, phase-locking analysis of the M3 muscarinic receptor-calcium signaling pathway was used to reveal the potential importance of basal IP3 production, a finding that has important implications on calcium response fidelity to periodic stimulation.
Instantaneous fabrication of arrays of normally closed, adjustable, and reversible nanochannels by tunnel cracking
TL;DR: A direct fabrication method capable of producing fully-reversible, tunable nanochannel arrays, without the use of a molding step, is described, based on tunnel cracking of a readily-prepared brittle layer constrained between elastomeric substrates.
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Patent
Microfluidic gravity pump with constant flow rate
Shuichi Takayama,Joseph Chang,Dongeun Huh,Xiaoyue Zhu,Brenda S. Cho,Gary D. Smith +5 more
- 18 Jul 2002
TL;DR: A microfluidic system employs a microchannel and a gravity driven pump comprising horizontally oriented fluid supply reservoirs which supplies fluid to the microchannel at a substantially constant rate as mentioned in this paper.
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Polyelectrolyte‐Clay‐Protein Layer Films on Microfluidic PDMS Bioreactor Surfaces for Primary Murine Bone Marrow Culture
Geeta Mehta,Mark J. Kiel,Jungwoo Lee,Nicholas A. Kotov,Jennifer J. Linderman,Shuichi Takayama +5 more
TL;DR: Modification of the surface of PDMS with biofunctional multilayer coatings is shown to promote marrow cell attachment and spreading and has advantages of greater flow control, automatic processing, multiplexed fabrication, and use of lesser amounts of polymers and protein solutions.
Rounded multi-level microchannels with orifices made in one exposure enable aqueous two-phase system droplet microfluidics.
TL;DR: The multi-level channels fabricated by backside lithography satisfy two conflicting needs: the requirement to have narrowed channels for efficient valve closure by channel deformation and the need to have wide channels to reduce the flow velocity, thus reducing the capillary number and enhancing droplet formation.
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